Biomaterials for Regenerative Medicine and Tissue Engineering

Dear Colleagues,

Regenerative medicine (RM) is a broad interdisciplinary field of medical sciences that deals with the possibilities to repair and regenerate damaged tissues and organs applying various technologies and approaches, with the use of biomaterials. Tissue engineering (TE) enables the replacement of damaged tissues and organs with new ones by combining cells, stimulating (inductive, instructive) factors and biomaterials such as scaffolds or carriers. TE interdisciplinary incorporates principles of biology, medicine, materials science, chemistry and engineering to create functional substitutes that mimic the structure and function of natural tissues. Research in the field of biomaterials has significantly advanced the fields of RM and TE. Important prerequisites for the biomaterial to be implanted are its biocompatibility and biofunctionality. Biomaterials used in tissue regeneration should enable the adhesion, migration, proliferation and differentiation of cells, i.e., they should mimic the natural structure of the extracellular matrix and represent a physiological microenvironment for normal cellular functions. Moreover, they should have adequate biodegradability properties to facilitate the formation and growth of new tissue.

This Special Issue seeks quality original research and review articles that highlight new insights into the fundamental cellular and molecular interactions with biomaterials for use in RM and TE, as well as the tissue and immune system responses to these biomaterials. Studies (in vitro, ex vivo, in vivo; preclinical and clinical) with new biomaterials that have been developed as implants, scaffolds, carriers and medical devices for use in therapeutic, diagnostic and other medical purposes are welcome. Submissions with considerations about materials of natural and synthetic origin, polymers, membranes, ceramics, composites and nanomaterials, especially if they are made with integrated bioactive components and as 3D printing and intelligent materials are welcome as well. We look forward to your contribution to this Special Issue, working on the development, improvement and advancement of the design and applications of biomaterials that push the boundaries of biological and medical possibilities.

Prof. Dr. Stevo Najman
Dr. Sanja Stojanović
Dr. Mike Barbeck
Guest Editors

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