Soft and Hard Tissue Regeneration II

A special issue of Biomedicines (ISSN 2227-9059).

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 3552

Special Issue Editors

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Guest Editor
Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, 18057 Rostock, Germany
Interests: bone substitutes; collagen-based biomaterials for soft and hard tissue regeneration; foreign body response to biomaterials; inflammation; macrophages; multinucleated giant cells, degradation processes of biomaterials; phagocytosis; vascularization; histology; immunohistochemistry; histomorphometry
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Guest Editor
Clinic for Dermatology and Venerology, Rostock University Medical Center, Strempelstr. 13, 18057 Rostock, Germany
Interests: wound healing; soft tissue regeneration; biomaterials; toxicity and compatibility testing; DNA repair; skin cancer; skin; melanoma mutation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although a broad number of medical devices for soft and hard tissue regeneration are already on the market, fundamental biological and medical aspects are still unclear. Moreover, most of these materials still do not possess regenerative capacities comparable to autologous transplants. Thus, it is of great importance to obtain deeper insights in the material-associated biological responses for the understanding of the clinical relevance of a specific biomaterial. Moreover, this knowledge, in concert with new results regarding new biomaterials or biomaterial classes, will lead to improved material development and clinical translation. Nowadays, a large number of preclinical in vitro and in vivo studies, as well as clinical studies, are being conducted to develop new biomaterials, with a focus on new material classes such as biodegradable metals or 3D-printed materials for different clinical applications. Furthermore, it is understood that the interaction of materials with the immune system is of high importance for the biofunctionality of biomaterials.

However, we still require deeper insights into different material-related processes. In this Special Issue, we aim to present new insights into the underlying cellular and molecular interactions of biomaterials for hard and soft tissue regeneration. We invite you to submit studies describing new biological aspects of both new and already available biomaterials, and innovative material-processing techniques related to the healing processes of soft and hard tissues. Contributions in the form of reviews and/or original papers are both welcome.

Dr. Ole Jung
Dr. Mike Barbeck
Prof. Dr. Steffen Emmert
Guest Editors

Manuscript Submission Information

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Published Papers (1 paper)

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13 pages, 3238 KiB  
Investigation on the Temperature Control Accuracy of a Print Head for Extrusion 3D Printing and Its Improved Design
by Peng Zhang, Qiang Gao, Kaicheng Yu, Yifeng Yao and Lihua Lu
Biomedicines 2022, 10(6), 1233; - 25 May 2022
Cited by 5 | Viewed by 2814
For the extrusion 3D printing process, the printing temperature has a significant impact on the filament formation process because the rheological properties of the printed materials are extremely thermal sensitive, which requires a high temperature control accuracy of the print head. This paper [...] Read more.
For the extrusion 3D printing process, the printing temperature has a significant impact on the filament formation process because the rheological properties of the printed materials are extremely thermal sensitive, which requires a high temperature control accuracy of the print head. This paper presents a numerical and experimental investigation on the temperature field of a homemade print head. A finite element simulation model for analyzing the temperature field of the print head was established, by which the temperature distribution inside the print head can be acquired. Moreover, to improve the temperature control accuracy, an improved configuration was proposed, and two schemes were compared. The temperature control error dropped from 28% to 6.2% with the improved print head, which was verified experimentally. Furthermore, printing trials were conducted by the optimized print head. The filament diameter could be regulated by changing the temperature of the print head, which validates the feasibility to control the filament diameter during the extrusion process via temperature regulation. Full article
(This article belongs to the Special Issue Soft and Hard Tissue Regeneration II)
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