Advances in Polymeric Biomaterials: Drug Delivery and Tissue Engineering II

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1570

Special Issue Editor


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Guest Editor
School of Pharmacy and Bioengineering, Keele University, Staffordshire ST5 5BG, UK
Interests: advanced biomaterials; especially hydrogel; drug delivery; additive manufacturing and 3D bioprinting
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polymeric biomaterials have played a pivotal role in recent advances in drug delivery and tissue engineering, and in promoting the healing process in regenerative medicine. These biomaterials provide the unique features and structural flexibility that enable us to tailor their physicochemical and mechanical properties according to the desired applications. Advances in our understanding of cell biology and organ tissue properties and functions have accelerated the development of sophisticated polymeric biomaterials with, for example, stimuli-responsive linkages suitable for on-demand or programmed drug delivery or tissue engineering scaffolds with biomimetic functional groups.

Additionally, the development of biomanufacturing processes (3D bioprinting, electrospinning, etc.) has provided a unique opportunity to shape natural and/or synthetic biomaterials into the desired geometry, with precise control over multiple compositions, spatial distributions, and architectural accuracy/complexity. These have also opened a new frontier in a relatively new concept of personalized medicine, where a custom-designed drug delivery device or an organ tissue implant embedded with cells can be fabricated to meet a patient’s individual health needs.

This Special Issue aims to highlight and promote recent advances in the synthesis, characterizations, and applications of innovative polymeric biomaterials in drug delivery and tissue engineering. It also covers the potential applications of such biomaterials in biofabrication, 3D bioprinting, surface bio-functionalization, and implantable devices and sensors. 

Dr. Pooya Davoodi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biopolymers
  • functional biomaterials
  • conductive biomaterials
  • drug/gene delivery
  • tissue engineering
  • regenerative medicine
  • microparticles
  • nanoparticles
  • nanomedicine
  • biomimetic scaffolds
  • extracellular matrix (ECM)
  • injectable polymers and hydrogels
  • hydrogels
  • polymeric implants
  • bio-adhesives
  • 3D bioprinting
  • 4D bioprinting
  • bio-inks
  • additive manufacturing
  • electrospinning
  • electrospraying
  • microfluidics
  • personalized medicine

Published Papers (1 paper)

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Research

20 pages, 6874 KiB  
Article
Laminar Biomaterial Composite of PVA Cryogel with Amnion as Potential Wound Dressing
by Łukasz Otulakowski, Agnieszka Klama-Baryła, Anna Celny, Maciej Kasprów, Anna Hercog, Marcin Godzierz, Anna Sitkowska, Sławomir Kadłubowski, Magdalena Jaworska, Ewa Chmielik, Barbara Trzebicka and Alicja Utrata-Wesołek
Polymers 2023, 15(13), 2955; https://doi.org/10.3390/polym15132955 - 05 Jul 2023
Cited by 1 | Viewed by 1183
Abstract
Gel dressings, composed of polymers both natural and synthetic, are successfully used in the treatment of burn wounds. They protect the burn wound site against adverse external factors, ensure an adequate level of tissue hydration, have soothing and pain-relieving properties, and also support [...] Read more.
Gel dressings, composed of polymers both natural and synthetic, are successfully used in the treatment of burn wounds. They protect the burn wound site against adverse external factors, ensure an adequate level of tissue hydration, have soothing and pain-relieving properties, and also support the healing process and reduce the risk of pathological scars. Another promising material that can be used in the wound-healing process is an amnion membrane. Due to its valuable properties such as protecting the body against bacterial infections and permeability to nutrition, it has found usage in different brands of medicine. In this work, we have combined the beneficial properties of hydrogels and amnion in order to make the laminar dressing that may serve for wound healing. For that purpose, the physically crosslinked cryogel of poly(vinyl alcohol) (PVA) was covered with an amnion membrane. Subsequently, gamma irradiation was performed, leading to the simultaneous internal crosslinking of the hydrogel, its permanent bonding with the amnion, and dressing sterilization. The physicochemical properties of the dressing including gel fraction, swelling, and hardness were studied. Biological tests such as the MTT assay, antimicrobial activity, and histopathological examination confirmed that the obtained material constituted a promising candidate for further, more in-depth studies aiming at wound dressing application. Full article
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