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Advanced Natural Polymers for Biomedical Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: 10 September 2025 | Viewed by 1052

Special Issue Editor


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Guest Editor
National & Local Joint Engineering Laboratory for New Petro-Chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China
Interests: natural polymers; hydroxyapatite; biopolymer composites; chitosan; cellulose; biomedical

Special Issue Information

Dear Colleagues,

Compared to synthetic polymers, natural polymers generally present superior biocompatibility and bioactivity and have great potential in biomedical applications.

This Special Issue aims to deliver new insights and report on recent progress in the field of natural polymers for biomedical applications. An important aspect of this Special Issue will be natural polymer-based membranes, scaffolds, hydrogels used in guided bone regeneration, wound surgical dressings, drug carriers, hemostatic materials, and so on, based on the natural polymer chemical reactivity or physical, chemical, structural, biological, pharmacological functionality, etc.

Authors are welcome to submit their latest results in this broad topic in the form of original full articles or reviews.

Prof. Dr. Liuyun Jiang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural polymers
  • natural polymer-based membranes
  • scaffolds
  • hydrogels
  • biomedical
  • bone regeneration
  • wound surgical dressing
  • drug carrier

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Published Papers (1 paper)

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Research

17 pages, 1904 KiB  
Article
Study on an Injectable Chitosan–Lignin/Poloxamer Hydrogel Loaded with Platelet-Rich Plasma for Intrauterine Adhesion Treatment
by Zhipeng Yu, Yang Min, Qi Ouyang, Yuting Fu, Ying Mao, Shuanglin Xiang, Xiang Hu and Liuyun Jiang
Polymers 2025, 17(4), 474; https://doi.org/10.3390/polym17040474 - 11 Feb 2025
Cited by 1 | Viewed by 798
Abstract
It is a great challenge to obtain an ideal hydrogel for the clinical treatment of intrauterine adhesion (IUA) disease. Here, a novel injectable chitosan–lignin/poloxamer hydrogel loaded with platelet-rich plasma (CL-PF127@PRP) was prepared by self-assembly at room temperature. Fourier transform infrared spectroscopy (FT-IR), scanning [...] Read more.
It is a great challenge to obtain an ideal hydrogel for the clinical treatment of intrauterine adhesion (IUA) disease. Here, a novel injectable chitosan–lignin/poloxamer hydrogel loaded with platelet-rich plasma (CL-PF127@PRP) was prepared by self-assembly at room temperature. Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), rheological analysis, and injectable writing were used to characterize the structure of the hydrogel. The results confirmed that the amino group of chitosan and the sulfonic group of sodium lignosulfonate were ionic-crosslinked by electrostatic attraction, which stabilized the three-dimensional structure of the PF127 hydrogel loaded with PRP, and PRP made the porous structure gradually become tight. Moreover, the CL-PF127@PRP hydrogel displayed good injectability and a solid state. The soaking experiment showed that the CL-PF127@PRP hydrogel had suitable degradation at pH = 7 and a good PRP release rate (PRP release 70% at 96 h). Cell experiments in vitro demonstrated that the CL-PF127@PRP hydrogel possessed good biocompatibility, an anti-inflammatory function, and pro-angiogenic activity. Furthermore, an animal experiment of skin wound and IUA confirmed that the skin wound closure rate of the CL-PF127@PRP hydrogel was over 50% on the seventh day. PRP improved the thickness of the endometrium and uterus receptivity, suggesting that the CL-PF127@PRP hydrogel offers great promise for the clinical treatment of IUA. Full article
(This article belongs to the Special Issue Advanced Natural Polymers for Biomedical Applications)
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