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Plant Essential Oils: Chemistry, Bioactivity and Applications
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Plant Essential Oils: Chemistry, Bioactivity and Applications

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 31 January 2027 | Viewed by 1052

Editors

Prof. Dr. Olivera Politeo

E-Mail Website
Guest Editor
Department of Biochemistry, Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, 21000 Split, Croatia
Interests: natural products; secondary plant metabolites; chemistry; essential oils; biological potential
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Ivana Generalić Mekinić

E-Mail Website
Guest Editor
Department of Food Technology and Biotechnology, Faculty of Chemistry and Technology, University of Split, 21000 Split, Croatia
Interests: food chemistry; herbs; natural extracts; antioxidants; antimicrobials; phytochemicals; phenolic compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although the use of aromatic and medicinal plants dates back to ancient times, it remains a key area of scientific interest for researchers across the world. Among the wide spectrum of plant metabolites, particular attention has been devoted to essential oils and their constituents due to their diverse and valuable organoleptic and biological properties.

In addition to biotic and abiotic factors that influence the chemical profile of essential oils, the methods applied for the pretreatment of plant material, the extraction of essential oil, and analytical characterization play a crucial role in determining their composition, bioactivity and potential applications across various industries. Essential oils of rare and poorly researched plant species are of particular interest. As Guest Editors of this Special Issue, “Plant Essential Oils: Chemistry, Bioactivity and Applications,” we are pleased to invite you to contribute an original research article or a review paper addressing recent advances and state-of-the-art knowledge in the field of plant essential oils and their chemistry and properties.

Prof. Dr. Olivera Politeo
Prof. Dr. Ivana Generalić Mekinić
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • essential oils
  • secondary plant metabolites
  • volatiles
  • chemical profile
  • gas chromatography
  • biological activity
  • application
  • by-products

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Published Papers (1 paper)

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Research

18 pages, 1011 KB  
Article
Essential Oil Composition and Biological Activities of Hyptis eriocephala, an Aromatic Lamiaceae Species from Southern Ecuador
by Diana Guaya, Ana Cristina Hernández and Vladimir Morocho
Plants 2026, 15(15), 2407; https://doi.org/10.3390/plants15152407 - 6 Aug 2026
Viewed by 120
Abstract
Hyptis eriocephala is an aromatic Lamiaceae species from southern Ecuador whose essential oil has not previously been characterized. To establish an initial phytochemical and biological baseline, aerial parts collected at Villonaco were subjected to three independent steam-distillation runs, yielding 0.13 ± 0.04% ( [...] Read more.
Hyptis eriocephala is an aromatic Lamiaceae species from southern Ecuador whose essential oil has not previously been characterized. To establish an initial phytochemical and biological baseline, aerial parts collected at Villonaco were subjected to three independent steam-distillation runs, yielding 0.13 ± 0.04% (w/w) essential oil. Volatile constituents were tentatively assigned by GC–MS using concordant EI mass-spectral and linear retention-index evidence, whereas relative composition was determined by GC–FID peak-area normalization without an internal standard, calibration curves, or response correction factors. Sixty-five constituents accounted for 96.81% of the total GC–FID peak area. The relative profile was dominated by hydrocarbon sesquiterpenes (67.88%), followed by hydrocarbon monoterpenes (24.36%), with α-copaene (28.20 ± 0.24%), germacrene D (9.29 ± 0.09%), α-pinene (6.98 ± 0.03%), α-cubebene (6.70 ± 0.06%), δ-cadinene (6.03 ± 0.07%), limonene (5.44 ± 0.05%), (E)-caryophyllene (5.31 ± 0.05%), and β-phellandrene (4.96 ± 0.02%) were the principal constituents. The oil showed a narrow antibacterial response, with MIC values of 250 µg/mL against Enterococcus faecium ATCC 27270 and 2000 µg/mL against Enterococcus faecalis ATCC 19433. Radical-scavenging activity was assay-dependent: activity was measurable in the ABTS assay (SC50 = 76.87 ± 1.05 µg/mL; TEAC = 30.06 ± 1.16 µM TE/g EO), whereas 50% DPPH scavenging was not reached at 8000 µg/mL. The oil preferentially inhibited BuChE (IC50 = 125.3 ± 1.03 µg/mL) over AChE (IC50 = 385.9 ± 1.02 µg/mL). These findings establish a preliminary phytochemical and biological baseline for the Villonaco material but do not demonstrate a species-wide chemotype, mechanism of action, or therapeutic potential. Full article
(This article belongs to the Special Issue Plant Essential Oils: Chemistry, Bioactivity and Applications)
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