Plant Extracts for Health Benefits and Nutrition

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 872

Special Issue Editor


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Guest Editor
Department of Hygiene, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan
Interests: medical science; plant extract; human health effect; chronotoxicity

Special Issue Information

Dear Colleagues, 

Plant extracts have gained significant attention for their potential health benefits in recent years. Many people are turning to natural remedies for various conditions, and plant-based extracts are often used in supplements, skincare, and even as part of traditional medicine practices. Although recent research has tended to focus on the pharmacological or toxicological effects of single substances, understanding the effects of crude extracts is an initial step in discovering effective compounds.

In this Special Issue, we invite the submission of full reviews, original research, and short communications related to health benefits and nutrition using in vivo and in vitro experiment. We also welcome not only crude extracts but also compounds identified from plant extracts. However, we do not accept work on the discovery of new compounds from plant extracts without functional evaluation. 

Dr. Hiroki Yoshioka
Guest Editor

Manuscript Submission Information

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Keywords

  • phytochemistry
  • medicinal plants
  • bioactive compounds
  • plant-derived drugs
  • cancer
  • heart disease
  • diabetes
  • obesity
  • liver disease
  • kidney disease
  • cerebrovascular disease
  • skin disease

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Published Papers (1 paper)

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Research

14 pages, 2493 KiB  
Article
Sasa veitchii Extract Mitigates Mycophenolate Mofetil-Induced Human Palatal Cell Proliferation Inhibition by Downregulating microRNA-4680-3p
by Hanane Horita, Yosuke Tsukiboshi, Kenichi Ogata, Aya Ogata, Hisaka Kurita, Shuji Yamashita, Hirotaka Yamashita, Naoki Inagaki, Hyogo Horiguchi and Hiroki Yoshioka
Plants 2025, 14(7), 1150; https://doi.org/10.3390/plants14071150 - 7 Apr 2025
Viewed by 381
Abstract
Cleft palate is a common birth defect worldwide and is caused by both genetic and environmental factors. Intrauterine drug exposure is one of the environmental factors that can induce cleft palate. Mycophenolate mofetil (MPM) is an immunosuppressant drug with teratogenic effects, including cleft [...] Read more.
Cleft palate is a common birth defect worldwide and is caused by both genetic and environmental factors. Intrauterine drug exposure is one of the environmental factors that can induce cleft palate. Mycophenolate mofetil (MPM) is an immunosuppressant drug with teratogenic effects, including cleft palate. However, the research on MPM-induced cleft palate remains limited. Sasa veitchii extract (SE), a medical plant extract, is commercially available in Asia and has been reported to show effectiveness against oral diseases. The purpose of the present study is to evaluate whether SE protects against MPM-induced immunosuppression in human embryonic palatal mesenchymal (HEPM) cells. Cell viability and G1 phase-related cell cycle markers were assessed by co-treatment with MPM and SE. Furthermore, we quantified cleft palate-associated miRNA levels and the expression of its downstream genes. MPM treatment reduced cell viability in a concentration-dependent manner. Co-treatment with SE alleviated MPM-induced inhibition of HEPM cell proliferation. Additionally, SE reduced MPM-induced miR-4680-3p upregulation and the downregulation of its downstream genes (ERBB2 and JADE1). These results suggest that SE alleviated MPM-induced cell proliferation inhibition through modulating miR-4680-3p expression. Full article
(This article belongs to the Special Issue Plant Extracts for Health Benefits and Nutrition)
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