Special Issue "Genetics and Functional Genomics in Cannabis sativa, L."
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 37450
Interests: Cannabis sativa secondary metabolism: identification and isolation of the structural and regulatory genes involved in cannabinoid, terpens, and flavonoids biosynthesis and accumulation. Valorisation of hemp waste as a source for the production of new biochemicals of pharmaceutical, cosmeceutical, and manufacturing interests. In vitro culture and micropropopagation of medical Cannabis. Influence of photoperiod on flowering time and seed set in Cannabis sativa
Cannabis sativa L. is a fascinating and, at the same time, controversial plant widely cultivated for diverse uses, spanning from the production of paper and textiles to pharmaceutical applications. Moreover, it is a low input, high sustainable crop, matching with bioeconomy principles and perfectly fitting in the current scenario of the climate crisis.
The recent interest in Cannabis cultivation, for a long time a neglected plant, derives from the fact that, in addition to being a good source of both cellulosic and woody fibers, it is particularly rich in secondary metabolites, conferring a high added-value to this plant. Female inflorescences are sources of peculiar bioactive compounds, but there are also phytocomplexes in which the beneficial activities of single molecules are potentiated by a synergic effect of the blend made of cannabinoids, terpens, and flavonoids. The molecular comprehension of their biosynthesis and regulation in Cannabis will allow for manipulating their content and to develop markers for breeding. Female inflorescences also produce seeds characterized by flavors and oil composition valuable for human consumption. The increase in grain yield and seed quality are important goals for hemp breeding, and require a deeper knowledge of the basic plant and floral biology, also at the molecular level.
In recent years, a great deal of Cannabis genomic and transcriptomic data have became available, providing the hemp research community with fundamental tools to identify target genes of interest, and with databases to interrogate in the search of candidate genes for a number of traits. Despite significant progress, however, much remains unknown regarding Cannabis genetics and functional genomics, still leaving a lot of room for study in different hemp research areas. A few genes have been identified, especially those involved in the biosynthesis of cannabinoids, but a functional characterization still lags behind for most of them.
This Special Issues, titled “Genetics and Functional Genomics in Cannabis sativa, L.” intends to collect papers ranging from genome-wide to target gene analyses on different hemp research topics. The identification of new genes involved in the synthesis of specialized metabolites or in the expression of other important traits for Cannabis breeding (fiber traits, flowering time, grain yield and quality, sex plasticity, disease resistance, etc.) are welcome, together with papers reporting on the development of methods for reverse genetics in Cannabis, and the characterization of functional target genes. Genome-wide bioinformatic analyses are also welcome, especially when they bring new knowledge about hemp research.
Dr. Roberta Paris
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- gene function
- resistance genes
- transcription factors
- tissue culture
- reverse genetics
- genome assemblies
- genomic resources
- flowering time
- sex expression
- genetic maps
- molecular biology
- gene knockout
- genetic transformation
- genetic diversity