Shining Light on Healing: Photobiomodulation Therapy

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 6

Special Issue Editor


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Guest Editor
Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil
Interests: low-level laser therapy (LLLT); photobiomodulation therapy (PBMT); transcranial photobiomodulation (t-PBM); myonecrosis; gait biomechanics; spectroscopy of biomolecules (Raman and FT-IR); molecular biology; diabetic neuropathic pain; neurophysiology; mitochondrial metabolism; affective components of chronic pain; anxiety; major depressive disorder (MDD)

Special Issue Information

Dear Colleagues,

Photobiomodulation therapy (PBMT), also known as low-level light therapy (LLLT), has gained significant attention over the past decades for its non-invasive approach to modulating biological processes using low-intensity light in the red to near-infrared spectrum. This therapy has demonstrated promising outcomes in promoting tissue repair, reducing inflammation, alleviating pain, and modulating immune and neurological functions. As our understanding of light–tissue interactions deepens, new applications and mechanisms of action continue to emerge, expanding the therapeutic potential of PBMT across diverse medical fields.

This Special Issue of Photonics aims to showcase recent advances in the science and clinical application of photobiomodulation therapy. We invite contributions that explore novel light sources, dosimetry protocols, molecular and cellular mechanisms, translational research, and clinical outcomes. Studies addressing interdisciplinary approaches, such as the integration of PBMT with neurorehabilitation, neuropsychiatry, immunomodulation, and regenerative medicine, are especially encouraged.

We welcome original research articles, reviews, and case reports from both academic and clinical researchers aiming to advance the field and foster dialogue across disciplines.

Topics include, but are not limited to, the following:

  • Mechanisms of action of PBMT at the cellular and molecular levels;
  • PBMT in neuroprotection and neuromodulation;
  • Applications in musculoskeletal and joint disorders;
  • Immune and anti-inflammatory effects of PBMT;
  • PBMT in wound healing and tissue regeneration;
  • Advances in light source technology and dosimetry;
  • PBMT in dentistry, dermatology, and oncology;
  • Combined therapies and integrative approaches involving PBMT.

Dr. Willians Fernando Vieira
Guest Editor

Manuscript Submission Information

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Keywords

  • photobiomodulation therapy (PBMT)
  • low-level light therapy (LLLT)
  • transcranial PBMT
  • light–tissue interaction
  • red light therapy
  • anti-inflammatory effects
  • tissue regeneration
  • neuromodulation
  • mitochondrial photostimulation
  • clinical applications of PBMT

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Published Papers

This special issue is now open for submission.
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