Recent Advances in Skin Drug Delivery
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 18296
Special Issue Editors
Interests: transdermal drug delivery; topical application; thermotropic liquid crystals; prodrugs for transdermal delivery
Interests: biological barriers; drug delivery systems; nanoparticles; liposomes
Special Issue Information
Dear Colleagues,
Skin drug delivery is associated with a convenient noninvasive, targeted, and on-demand route of administration for the treatment of various diseases. Although skin constitutes an ideal platform to achieve both local and systemic effects of drug substances, skin drug delivery remains challenging due to the protective properties of the skin barrier, which consequently often limits the penetration and permeation of drug molecules.
A variety of methods have been developed to investigate and eventually improve skin penetration and permeation, including chemical enhancers, novel formulations and physical approaches. Improved penetration-enhancement strategies led to a resurgence of interest in transdermal drug delivery to the systemic circulation. Given that only a small number of transdermal formulations are commercially available, further advancement of skin drug delivery requires the development of novel delivery systems and approaches that are suitable for compounds distinguished by physicochemical properties and molecular sizes.
Undoubtedly, any targeted and active skin drug delivery vision promoting increased drug bioavailability should comprise an encouraging approach for the safe and efficient transfer of therapeutic molecules. On the other hand, no less important is the delivery of topical drugs directly to various skin structures with minimal penetration into the systemic circulation.
This Special Issue aims to provide readers with the recent advancements in drug delivery across the skin, for both topical and systemic applications. We welcome the submission of original research and review articles focused on the above-described subjects.
Dr. Iryna Kravchenko
Prof. Dr. Claus-Michael Lehr
Dr. Mariia Nesterkina
Guest Editors
Manuscript Submission Information
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Keywords
- skin drug delivery
- permeation and penetration
- physical and chemical enhancers
- nanoparticles and nanocarriers
- 3D printed forms
- microneedles
- liquid crystals
- sustained/controlled release
- therapy ultrasound
- liposomes
- topical application
- skin segmentation
- phospholipids
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