Population Pharmacokinetics and Pharmacogenetics

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 63

Special Issue Editor


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Guest Editor
College of Pharmacy, Sunchon National University, 255 Jungang-ro, Suncheon-si 57922, Jeollanam-do, Republic of Korea
Interests: pharmacokinetics; pharmacodynamics; toxicometrics; risk assessment; physiologically based modeling; lymphatic delivery; nanoformulation and evaluation; bioanalytical method development and validation
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Special Issue Information

Dear Colleagues,

The approach to precision medicine that minimizes the side effects of drugs and maximizes their effectiveness has been a scientific challenge that has persisted for a long time. To realize precision medicine, pharmacometric studies have been actively progressing recently, and in particular, various attempts are being made to quantitatively interpret pharmacokinetic variability between individuals. Interpretations of pharmacokinetic variability between individuals can be approached in relation to various physiological, biochemical, and genetic factors, and the new discovery of valid covariates is greatly helping to visualize the possibility of precision medicine.

This Special Issue focuses on mathematical modeling related to the discovery of effective covariates, population pharmacodynamic modeling, and genetic polymorphism in the interpretation of pharmacokinetic variability between individuals. Therefore, pharmacokinetics, pharmacodynamics, in vivo drug quantification, and genetic polymorphism studies (such as enzymes or transporters involved in drug absorption, distribution, metabolism, and excretion) for precision medicine and individualized pharmacotherapy settings will be suitable for the scope of this Special Issue . In addition, studies on predicting drug behavior and efficacy in the body through mathematical modeling, exploring clinical usage based on models, and exploring effective covariates to explain the diversity of pharmacokinetics and pharmacodynamics among individuals will be very welcome. Finally, it is expected that a great deal of useful and interesting research information for the realization of precision medicine will be introduced in this Special Issue.

Dr. Seung-Hyun Jeong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pharmacokinetics
  • pharmacogenetics
  • precision medicine
  • population pharmacometrics model
  • mathematical modeling
  • dosage regimen
  • inter-subject variability

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Published Papers

This special issue is now open for submission.
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