Multidrug-Resistant Staphylococcus aureus
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 4551
Special Issue Editor
Special Issue Information
Dear Colleagues,
Staphylococcus aureus is a Gram-positive cocci arranged in grape-like clusters that is a common inhabitant of the skin and upper respiratory tract in humans and animals. Although S. aureus is considered to be a common commensal of the human microbial flora, it can act as an important pathogen. S. aureus is a common cause of various skin and soft tissue infections including boils, impetigo, folliculitis and scalded skin syndrome. S. aureus is also implicated in bone and joint infections, bacteremia, pneumonia, food poisoning and fatal infections such as toxic shock syndrome. It is estimated that more than 50,000 deaths in the USA alone are associated with S. aureus infections. The treatment of S. aureus infections may be difficult due to ever-emerging antibiotic-resistant strains. Methicillin-resistant Staphylococcus aureus (MRSA) has become a difficult pathogen to combat, especially when it exhibits multidrug-resistant attributes to drugs currently used for treatment other than beta-lactams (e.g., vancomycin, gentamicin, linezolid or clindamycin). Thus, MRSA has been commonly associated with hospital-acquired Staphylococcus aureus infections (HA-Staphylococcus aureus) and is frequently increasing in community-associated Staphylococcus aureus infections (CA-Staphylococcus aureus). It is believed that infection due to MRSA is the second leading cause of mortality associated with antimicrobial resistance in recent years. Mechanisms of antimicrobial resistance in S. aureus vary between enzymatic inactivation of the antibiotic, alteration of the target, and trapping of the antibiotic and the efflux pump.
For this Special Issue, we invite you to send original or review papers on various aspects of multidrug-resistant Staphylococcus aureus.
Prof. Dr. Hussein Hasan Abulreesh
Guest Editor
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Keywords
- Staphylococcus aureus infections and antimicrobial resistance
- hospital-acquired Staphylococcus aureus infections and antimicrobial resistance
- community-associated Staphylococcus aureus infections and antimicrobial resistance
- antimicrobial-resistant Staphylococcus aureus
- resistance mechanisms in Staphylococcus aureus
- epidemiology of multidrug-resistant Staphylococcus aureus
- association between biofilm and multidrug resistance in Staphylococcus aureus
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