Dengue Virus: Transmission, Pathogenesis, Diagnostics, and Vaccines
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 2
Special Issue Editors
2. Department of Tropical Viral Vaccine Development, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan
Interests: serology and molecular epidemiology of arboviruses; diagnostics; anti-viral drugs; vaccine development
Special Issues, Collections and Topics in MDPI journals
Interests: therapeutic antibody production; vaccine development; emerging infectious diseases
Interests: arbovirus; tropical and infectious diseases; AMR; ethics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The number of dengue virus infections has been increasing dramatically and is becoming a serious challenge to global public health. Estimated 390 million infections occur annually, with above 100 million symptomatic cases from more than 120 countries worldwide. Rising urbanization, global travel, climate change, global warming, and migration of people due to extensive trade and tourism have created ample opportunities for expansion of mosquito’s vectors to diverse geo-climatic regions, thereby spreading dengue disease on a wider global scale. Dengue virus is tansmitted to humans through the bite of infected Aedes species mosquitoes, mainly A. aegypti and A. albopictus. Despite decades of research, there are currently no approved antiviral drugs or no safe and effective vaccines for the prevention and treatment of dengue infections. Qdenga® (TAK-003) is the only approved dengue vaccine, recommended by World Health Organization for children aged 6–16 in high-transmission areas, given in two doses three months apart. Hence, it is crucial to explore and determine virus, vector, and host factors that enhance dengue virus diseases in order to improve our epidemiological understanding or severity mechanisms, vaccines development, and antiviral drug discovery.
In this Special Issue, we aim to assemeble a collection of research papers and reviews that consider serological and molecular diagnostic approaches for dengue virus infections, virus-host interactions, and viral pathogenesis in animal models in order to promote the discovery of antiviral drugs and vaccines. The collection of papers in this Special Issue is expected to anhance our understanding and aid in the existing literature.
We look forward to your submissions.
Dr. Mya Myat Ngwe Tun
Prof. Dr. Takeshi Urano
Dr. Shyam Prakash Dumre
Guest Editors
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Keywords
- dengue virus infection
- serology
- molecular epidemiology
- antiviral drugs and vaccines against dengue virus
- dengue virus pathogenesis
- dengue virus vivo models
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