Special Issue "The Relationship between Diet and Hormones"
Deadline for manuscript submissions: closed (31 March 2020).
Interests: nutrition; stress; exercise; polyphenols and steroid hormones
Special Issues and Collections in MDPI journals
Diet is important when it comes to hormones because the energy and nutrients you obtain from food represent the raw materials to produce hormones and fuel your body. For example, all steroid hormones (>5 classes) are derived from cholesterol, which is mainly obtained from one’s diet. Hormonal changes influence all of us at every stage of life, and the effect is definitely variable between individuals. A huge number of clinical studies and hormonal research have now associated plant-based diet intake (especially rich in Polyphenols) with various beneficial health and biological activities. Functional foods and supplements have been found to reduce risk of chronic diseases, such as coronary heart disease, stroke, type 2 diabetes, obesity, neurodegenerative disorders, and some cancers. The pleiotropic effects of these polyphenols were evident as to their role in redox modulation and inflammatory processes, molecular signalling, stem cell proliferation and differentiation, metabolism regulation and hormonal imbalance, potential effect in cancer and neurodegenerative diseases, in addition to their known protective effects in lowering cardiovascular disease risk factors and blood pressure through their antioxidant properties. The mechanisms for the biological actions of diet and its active natural components have been mainly attributed to their multiple actions affecting various cellular and hormonal pathways. For example, the mechanisms by which natural products could exert their antihypertensive effect have shown a multiplicity of actions (e.g., increased NO production, inhibition of renin release and ACE activity, angiotensin receptor and calcium channel blockade, antioxidant and anti-inflammatory activities, and opioid agonistic effect). In addition, we have shown that polyphenols-rich pomegranate, dark chocolate, and green coffee can inhibit 11B-HSD1 activity, thereby improving mood and reducing stress by causing a reduction in blood pressure and the levels of the stress hormone cortisol.
A well-balanced diet has an enormous impact on many hormonal systems and aspects of our health, and a consensus about how and what to eat remains elusive. There are several factors related to diet that may cause hormonal imbalance and thus disease—for example, food allergy, overweight and obesity, inflammation caused by poor diet and sedentary lifestyle, sleeping patterns, digestive issues, and others. Researchers are now suggesting that circulating substances derived from the diet may exert direct and indirect actions to activate receptors and signalling pathways as well as providing fuel and micronutrients. Therefore, food may be considered as a cocktail of “hormones”. For example, high-fat diets cause weight gain by activating specific fatty acid receptors in the brain, and there is evidence that some dietary fatty acids also modify the actions of classical hormones such as ghrelin. Ghrelin can increase food intake and weight gain by binding to its receptor, growth hormone secretagogue receptor. However, for ghrelin to signal effectively, a fatty acid must first be attached to the peptide as a side chain.
Topics that are relevant to this Special Issue include all research topics related to the relationship of the diet and hormonal synthesis, release, metabolism, and action. The following are examples for interested authors:
- Cancer, diet, and hormones;
- Glucose metabolism, diabetes, hormones, and diet;
- Stress (acute and chronic), diet, and hormones;
- Hormonal changes as they relate to cognition, ageing, and diet;
- Cardiovascular disease, diet, and hormones;
- Diet and menopause in women;
- Gut hormones, diet, and brain;
- Adaptogens, e.g., liquorice and steroid hormones;
- Hormones and psychology; behaviour, biopsychology and health psychology in relation to Steroid hormones, love hormone (Oxytocin), and others;
- Vitamin D as a hormone: From vitamin D to hormone D: Fundamentals of the vitamin D endocrine system essential for good health.
Prof. Dr. Emad Al-Dujaili
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Vitamin D