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Nutrients
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Nutritional Strategies for Promoting Arterial Health and Cardiovascular Prevention
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Nutritional Strategies for Promoting Arterial Health and Cardiovascular Prevention

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 January 2026 | Viewed by 1088

Special Issue Editors

Dr. Iván Cavero Redondo

E-Mail Website
Guest Editor
CarVasCare Research Group, Faculty of Nursing, University of Castilla-La Mancha, Cuenca, Spain
Interests: dietary habits; nutrient impact; dietary interventions; inflammatory response; antioxidant nutrients; biomarkers; arterial stiffness; cardiovascular diseases; meta-analysis; diabetes; vascular health; hypertension
Special Issues, Collections and Topics in MDPI journals
Dr. Alicia Saz-Lara

E-Mail Website
Guest Editor
Health and Social Research Center, Universidad de Castilla-La Mancha, 16071 Cuenca, Spain
Interests: dietary habits; nutrient impact; dietary interventions; inflammatory response; antioxidant nutrients; arterial stiffness; vascular health; hypertension; cardiovascular diseases; diabetes; meta-analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Maintaining arterial health is fundamental to preserving cardiovascular function and reducing the global burden of heart-related diseases. Arterial health refers to the structural integrity and functional capacity of the arteries, which are essential for proper blood flow and the prevention of conditions such as atherosclerosis, hypertension, and stroke. Emerging research continues to highlight the critical role of nutrition in influencing vascular function, with specific nutrients and dietary patterns shown to exert either protective or detrimental effects on arterial integrity.

This Special Issue aims to explore the latest advances in nutritional strategies that support arterial health. We welcome original research and reviews that examine the mechanisms by which dietary components affect endothelial function, arterial stiffness, inflammation, lipid metabolism, and blood pressure regulation. Understanding these complex interactions is key to developing effective, evidence-based nutritional interventions for cardiovascular disease prevention. 

Dr. Iván Cavero Redondo
Dr. Alicia Saz-Lara
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • arterial health
  • cardiovascular wellness
  • atherosclerosis
  • hypertension
  • stroke prevention
  • dietary habits
  • nutrient impact
  • vascular function
  • cardiovascular risks
  • dietary interventions
  • arterial stiffness
  • endothelial function
  • oxidative stress
  • inflammatory response
  • antioxidant nutrients

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Published Papers (2 papers)

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Research

20 pages, 2300 KB  
Article
Relationship of Mediterranean Diet and Its Components with Parameters of Structure, Vascular Function, and Vascular Aging in Subjects Diagnosed with Long COVID: BioICOPER Study
by Alicia Navarro-Cáceres, Leticia Gómez-Sánchez, Silvia Arroyo-Romero, Nuria Suárez-Moreno, Andrea Domínguez-Martín, Cristina Lugones-Sánchez, Susana González-Sánchez, Emiliano Rodríguez-Sánchez, Luis García-Ortiz, Marta Gómez-Sánchez, Elena Navarro-Matias and Manuel A. Gómez-Marcos
Nutrients 2025, 17(20), 3226; https://doi.org/10.3390/nu17203226 - 14 Oct 2025
Viewed by 370
Abstract
Introduction: Long COVID (LC) is associated with an increase in cardiovascular risk and chronic inflammation, whereas the Mediterranean Diet (MD) seems to improve the aforementioned factors. The aim of this study is to analyse the relationship between MD and its components with vascular [...] Read more.
Introduction: Long COVID (LC) is associated with an increase in cardiovascular risk and chronic inflammation, whereas the Mediterranean Diet (MD) seems to improve the aforementioned factors. The aim of this study is to analyse the relationship between MD and its components with vascular structure, function, and aging in patients diagnosed with LC globally and by sex. Methods: This study was a cross-sectional study with 304 subjects diagnosed with LC; 207 were women and 97 men. Adherence to MD was evaluated with a validated MEDAS questionnaire, composed of 14 items. The vascular structure was assessed using carotid intima-media thickness (cIMT). Three measurements were carried out to evaluate vascular function: cardio-ankle vascular index (CAVI), brachial-ankle pulse wave velocity (baPWV), and carotid-femoral pulse wave velocity (cfPWV). Vascular aging index (VAI) was estimated. Results: The MD score was 7.80 ± 2.33, with no difference between sexes. Vascular function and aging parameter values were higher in men than in women. Use of olive oil as the principal source of fat for cooking, and consuming <1 serving of butter/day and <1 sugar-sweetened beverage/day showed >90% adherence. Logistic regression analysis displayed associations between cIMT < 0.625 and use of olive oil in the global analysis (OR = 0.148) and among men (OR = 0.120), and <2 commercial pastries/week in global (OR = 0.536). cfPWV < 7.400 m/s was associated with DM score ≥ 8 in global (OR = 0.444) and in women, as well as with <2 pastries/week in women (OR = 0.405). baPWV < 12.315 m/s was associated with ≥3 servings of pulses/week in global (OR = 0.481) and among women, as was <2 pastries/week in global (OR = 0.471) and in women. CAVI < 7.450 was associated with ≥4 tablespoons of olive oil/day in men. VAI < 63.693 was associated with DM score ≥ 8 in global (OR = 0.458) and in women, as well as <2 pastries/week in global (OR = 0.392). Conclusions: Adherence to MD was associated with lower cfPWV and VAI measures in the global analysis and among women. In particular, several of the components were associated with a better vascular profile in LC patients. Full article
(This article belongs to the Special Issue Nutritional Strategies for Promoting Arterial Health and Cardiovascular Prevention)
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13 pages, 530 KB  
Article
Influence of Adherence to the Mediterranean Diet on Vascular Health and Healthy Aging in Women: Assessment Using CAVI
by Inés Llamas-Ramos, Rocío Llamas-Ramos, María Cortés Rodríguez, Emiliano Rodríguez-Sánchez, Manuel A. Gómez-Marcos, Marta Gómez-Sánchez and Leticia Gómez-Sánchez
Nutrients 2025, 17(18), 2963; https://doi.org/10.3390/nu17182963 - 16 Sep 2025
Viewed by 567
Abstract
Background: Vascular aging, characterized by a progressive increase in arterial stiffness, is associated with an increased risk of cardiovascular disease. The Mediterranean diet (MD) has been shown to have protective effects on cardiovascular health, but its relationship with vascular aging, as assessed by [...] Read more.
Background: Vascular aging, characterized by a progressive increase in arterial stiffness, is associated with an increased risk of cardiovascular disease. The Mediterranean diet (MD) has been shown to have protective effects on cardiovascular health, but its relationship with vascular aging, as assessed by the Cardio-Ankle Vascular Index (CAVI), is not yet well established. Objective: To analyze the association between adherence to the MD and vascular aging estimated with CAVI in a sample of Spanish women with no history of previous cardiovascular disease. Methods: A cross-sectional study was conducted in 1468 women (aged 30–80 years), classified into three categories according to CAVI: healthy vascular aging (HVA), normal (NVA), and early (EVA). Adherence to the MD was assessed using the MEDAS questionnaire validated in Spain. ANOVA and chi-square tests were used to compare baseline characteristics, and multinomial logistic regression was used to analyze the association between MD adherence and vascular aging status, adjusting for age, sex, and drug treatment. Results: The CAVI increased progressively with age (p < 0.001) and was associated with higher blood pressure, dyslipidemia, hyperglycemia, and diabetes mellitus. Adherence to the MD was significantly higher in groups with lower arterial stiffness (p < 0.001). In the multivariate analysis, greater adherence to MD was associated with a higher probability of healthy vascular aging compared to NVA (OR: 1.872; 95% CI: 1.366–2.566; p < 0.001) and EVA (OR: 1.738; 95% CI: 1.363–2.218; p < 0.001). Conclusions: Greater adherence to the MD is associated with a healthier vascular aging profile. Promoting this dietary pattern may be an effective strategy for preventing arterial stiffness and reducing the cardiovascular risk associated with aging. Full article
(This article belongs to the Special Issue Nutritional Strategies for Promoting Arterial Health and Cardiovascular Prevention)
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