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Vitamin D Status and 25(OH)D Thresholds: From Musculoskeletal to Systemic and Beyond

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 25 June 2026 | Viewed by 1

Special Issue Editor


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Guest Editor
Department of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, 2/a Korányi S. Str, 1083 Budapest, Hungary
Interests: calcium metabolism; bone metabolism; genetics of bone diseases; vitamin D metabolism; pathophysiology; genetic of thyroid diseases; general health sciences; theoretical medicine
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Special Issue Information

Dear Colleagues,

Vitamin D deficiency is highly prevalent worldwide. Efforts to address this public health issue are mostly hindered by the heterogeneity of nutritional and clinical vitamin D guidelines. The importance of vitamin D extends far beyond musculoskeletal health. In fact, vitamin D is a precursor to the hormone 1,25-dihydroxyvitamin D, also known as the D hormone. Because the receptor (VDR) of this steroid hormone is expressed in most human cells, some scholars have proposed that vitamin D plays a more widespread role in general health. This idea is supported by several experimental and epidemiological studies. The general dilemma regarding the potential extraskeletal health benefits of vitamin D is that vitamin D requirements for skeletal health may differ from requirements for certain extraskeletal health benefits.

This Special Issue will include manuscripts focusing on assessing vitamin D status (i.e., deficiency, normal, or high levels) and investigating associations or causal relationships with health benefits or disease outcomes. Additionally, we accept manuscripts investigating vitamin D supplementation in healthy individuals or patient populations with vitamin D deficiency compared to individuals with normal vitamin D status.

Prof. Dr. István Takács
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 25(OH)D level
  • 1,25(OH)2D level
  • vitamin D deficiency
  • vitamin D supplementation treatment
  • prevention

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Published Papers

This special issue is now open for submission.
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