Maternal Nutritional-Mediated Programming of Offspring Health and Disease
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".
Deadline for manuscript submissions: closed (21 December 2023) | Viewed by 22678
Special Issue Editors
Interests: metabolic disorders; reproductive health; maternal-infant nutrition
Special Issue Information
Dear Colleagues,
Nutrition is unquestionably one of the cornerstones of growth, development, and health, and as such, maternal nutrition is of critical importance. The field of developmental origins of adult health and disease has incorporated this phenomenon and portends that maternal nutritional insufficiency as well as nutrient excess impact fetal/infant growth, leading to ‘programmed’ adult diseases. The essential principles which underlie the concept of programming are that nutritional manipulations cause different effects at different times in early life, rapidly growing fetuses and neonates are more vulnerable to these manipulations, and these manipulations have permanent effects. The permanent effects include altered organ structure, resetting of hormonal axes, as well as cellular, molecular, signaling, and epigenetic modifications.
The objective of this proposed Special Issue is to publish seminal papers (reviews, clinical and experimental studies) on the consequences of sub-optimal maternal nutrition prior to pregnancy and during pregnancy/lactation on offspring risk of disease. These include the development of a wide range of diseases such as metabolic abnormalities, reproductive dysfunction, cardiovascular disease, neurobehavioral and immunological disorders, allergies, and aging, to name a few. To mitigate the burden of chronic disease worldwide, a comprehensive understanding of nutrition-mediated programmed effects and mechanisms is imperative. Importantly, there are also significant implications for the generational transmission of disease.
Dr. Mina Desai
Prof. Dr. Michael Ross
Guest Editors
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