Precise Nutrition Therapy to Inflammatory Bowel Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 20 June 2025 | Viewed by 516
Special Issue Editor
Interests: clinical nutrition; immunology; molecular biology; physiology; irritable bowel syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nutritional deficiencies are common in patients with inflammatory bowel disease (IBD). However, the potential of precise nutrition therapy to prevent and treat malnutrition and intestinal failure in IBD, particularly in Crohn’s disease, offers a hopeful outlook. The increased requirements of energy and protein, especially in young children and adolescents with retarded growth, underscore the importance of this approach. Furthermore, the common occurrence of iron deficiency in Crohn’s disease and the necessity for proper forms and sufficient iron supplements in parenteral nutrition highlight the potential of nutritional therapy in IBD management.
Recent studies have provided insights into the efficacy of dietary interventions, such as exclusive or partial enteral or parenteral nutrition combined with oral feeding if possible. The nutrition therapy should include all required nutrients and functional bioactive compounds such as antioxidants, fat modifiers (if necessary), fish oil, and other resources of n-3 fatty acids, butyrate, prebiotics, and probiotics to maintain remission in IBD, especially in severe Crohn’s disease. Although not all the underlying mechanisms are known in the pathology of IBD, there is some evidence regarding medical nutritional therapy in this group of patients.
Understanding the nutrient requirements for patients with IBD is crucial. It not only informs our approach to nutritional therapy, but also guides our research into novel immune-modulatory compounds in safe doses. Improving patient motivation and adherence to various types of nutrition therapy or their combinations is a promising but challenging aspect of managing ulcerative colitis and Crohn’s disease. This emphasis on understanding and knowledge is key to our collective efforts in IBD management.
Dr. Mahsa Jalili
Guest Editor
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Keywords
- inflammatory bowel disease
- enteral nutrition
- parenteral nutrition
- malnutrition
- immunomodulation
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