Special Issue "100 Years of Bacteriophage: From Basic Research to Medical Application"
A special issue of Methods and Protocols (ISSN 2409-9279).
Deadline for manuscript submissions: closed (31 December 2018)
A century ago, Félix d’Hérelle coined the term bacteriophage. Since then, bacteriophage research has paved the way for major scientific breakthroughs such as the identification of DNA as the genetic material, the triplet nature of the genetic code, and the elucidation of the structure of DNA. The phenomenon of "restriction-modification", a phage defense mechanism, gave rise to the field of molecular biology, which, at present, is being revolutionized by the application of "CRISPR", which is also a phage defense mechanism. Molecular tools based on various phage-encoded proteins or whole phage particles, initially developed for basic research, are moving towards practical applications such as phage display for antibody engineering or diagnostics, capsid-based nanoparticles as drug-delivery vehicles and next-generation therapeutics, nano-films with anti-bacterial properties, bio-imaging, and rapid pathogen identification. Furthermore, the therapeutic use of bacteriophages to fight pathogenic bacteria, an idea as old as the discovery of phages, turned out to be a valid treatment alternative when antibiotics fail.
For this Special Issue of Methods and Protocols, we invite submissions of research manuscripts, protocols and review articles that focus on methods and techniques for basic bacteriophage research and phage applications.
Dr. habil. Hansjörg Lehnherr
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Methods and Protocols is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) is waived for well-prepared manuscripts submitted to this issue. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- plaque assay
- phage therapy
- phage display
- drug delivery
- animal model
- animal husbandry
- food processing
- human health