Special Issue "Noncovalent pi-Interactions"
Deadline for manuscript submissions: closed (30 April 2015)
Supramolecular chemists rely on the comprehension of non-covalent forces, which are the basis of highly specific recognition, transport, and regulation mechanisms. The orchestration of many chemical and biological processes is often dominated by an intricate combination of non-covalent interactions, which are the foundation of the life process itself, the most significant expression of function. By means of modern synthetic methods, organic/inorganic chemists can prepare host compounds for virtually guest any target molecule, even in very competitive medium. The action and development of drugs is the realm of medicinal chemistry, for which the understanding of noncovalent interactions is crucial for the rational design of new drugs.
The correct description of interactions between molecules is needed for the understanding and progress of the supramolecular chemistry that usually relies on strong, directional interactions, such as hydrogen bonding and halogen bonding, and less on directional forces like ion pairing. In addition, non-covalent interactions involving aromatic rings are enormously significant in this field. They play a crucial role in chemistry and biology, in particular drug–receptor interactions, crystal engineering, catalysis, transport, enzyme inhibition and protein folding. The continuous research on well-known cation–π, C–H/π, and π–π stacking interactions, less-known anion–π and lone pair–π interactions and other basically unknown like salt-bridge–π interactions is a good indication of the increasing interest by the scientific community on this topic.
Research articles covering all areas noncovalent interactions involving π-systems, such as crystal engineering, host-guest chemistry, catalysis, transport, or structural, computational, or biochemical matters, etc. are welcomed for inclusion in this Special Issue of Molecules.
Prof. Dr. Antonio Frontera
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cation-pi interactions
- anion-pi interactions
- pi-acidic interactions
- pi-basic interactions
- donor-acceptor interactions
- unconventional pi interactions
- pi-hole interactions