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Special Issue "Development of New Methods of Synthesis of Heterocycles"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 31 October 2019

Special Issue Editors

Guest Editor
Prof. Dr. Paula Sério Branco

LAQV-REQUIMTE, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal
Website | E-Mail
Interests: organic synthesis; heterocyclic compounds; natural products synthesis; dye-sensitized-solar-cells; catalytic sustainable procedures; new synthetic methods
Guest Editor
Dr. Filipa Siopa

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal
Website | E-Mail
Interests: C-H Activation; flow chemistry; total synthesis; heterocyclic compounds; organocatalysis

Special Issue Information

Dear Colleagues,

Heterocyclic compounds, cyclic compounds that have atoms of at least two different elements as members of their ring, are unavoidable structures due to the wide diversity of their applications. Nature is prodigious and creative in offering a huge amount of diverse heterocyclic compounds, such as nucleic acids, antibiotics, anticancer agents, agrochemicals, pharmaceuticals, pigments and others, that chemists use as the lead compounds to create even more diversity. Interest in this type of structure comes from the proprieties they impart to materials due to their polarity, solubility, and electronic properties. “Development of New Methods of Synthesis of Heterocycles” is a Special Issue of Molecules accepting manuscripts addressing the synthesis of natural and unnatural heterocyclic compounds with potential biological applications or heterocyclic new materials with singular proprieties. Original research articles or reviews that discuss alternative, new and innovative sustainable organic reactions and methodologies and employing alternative energy sources are welcome.

Prof. Paula Branco
Dr. Filipa Siopa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • heterocycles
  • synthetic methods
  • annulations
  • C–H activation
  • cross-coupling reactions
  • multicomponent reactions
  • condensation reactions
  • ring-closing reactions
  • solvent-free reactions
  • non-conventional reaction media
  • microwaves
  • sonication
  • electrosynthesis
  • photochemical and photocatalysis
  • metal–organocatalysis
  • biocatalysis and biotransformations
  • mechanochemical mixing
  • high-speed ball milling
  • Flow chemistry

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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