Special Issue "Autofluorescence Spectroscopy and Imaging"
Deadline for manuscript submissions: 30 September 2019
Dr. Anna Cleta Croce
Intitute of Molecular Genetics, National Research Council (IGM-CNR), c/o Department of Biology and Biotechnology, University of Pavia, Pavia, Italy
Website | E-Mail
Interests: photobiology; near UV-visible autofluorescence analysis; dysregulated metabolism; endogenous fluorophores; label free-real time diagnosis; fluid optical biopsy
Light induced emission from organic compounds was initially observed in the early 1800s, and was called “dispersive reflexion”, until George Stokes coined the new word, “fluorescence”, in 1852. Finally, it was named “autofluorescence” when it was detected using the newly developed fluorescence microscope early in 1900s. Since then, the ubiquitously presence in the whole life kingdom of the numerous fluorescing biomolecules and their relationship with normal or diseased conditions, in parallel to the technological advances, inspired so many unceasing studies, that it is impossible to describe them all. Within the various fields of studies for label free, in situ, real time analytical applications, biomedicine played an important role. This relied on quite a few endogenous fluorophores. For example, the loss or accumulation of collagen may account for the detection of cancer in multilayered epithelia or in disorders such as fibrosis, respectively; NADH and flavins reveal changes in the cell energy metabolism and redox state; lipofuscins reflect retinopathy, or more generally the gathering of hazardous oxidative events in metabolic disorders; and advanced glycation products in the skin reflect pathologies such as diabetes, cardiac or renal failure. In any case, their applications are far from being able to fully exploit the huge potential of autofluorescence, considering the advances in the analytical devices and methods, including time-resolved and multispectral imaging, microendoscopy, and procedures for label-free, even slide-free, timely, and cost effective automated diagnosis. Various, additional fluorescing biomolecules also suggest that beyond the progress in biomedicine, we cannot overlook the potential of autofluorescence applications in fields ranging from the surveillance of alimentary goods, to plant pathology and environment pollution.
Therefore, this Special Issue is aimed at attracting contributions on autofluorescence in its various aspects, not excluding technological development, to further promote the application of wide ranging label-free analytical procedures.
Dr. Anna Cleta Croce
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Cultured cells
- Animal tissues and organs
- Energy/lipid metabolism
- Oxidative stress
- Optical redox
- Imaging and FLIM
- Time resolved analysis
- Multiphoton excitation
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
- Author: Derrick Z.Y. Yong
Affiliation: A-Star, Singapore Institute of Manufacturing Technology, Precision Measurements Group, Singapore City, Singapore
- Author: Tilo Wünsch
Affiliation: Charité – Universitätsmedizin Berlin, Visceral and Transplantation Surgery, Berlin, Germany
- Author: Jose Manuel De La Rosa Vazquez
Affiliation: Instituto Politécnico Nacional, Unidad Zacatenco, Mexico City, Mexico
- Author: Darine Abi-Haidar
Affiliation: Universite Paris 7- Denis Diderot, Paris, France
- Author: Baharudin Abdullah
Affiliation: School of Medical Sciences - Universiti Sains Malaysia, Department of Otolaryngology-Head and Neck Surgery, Kubang Kerian, Malaysia
- Author: Klaus K.J. Hallfeldt
Affiliation: Ludwig-Maximilians-Universität München, Campus Innenstadt, Munich, Germany