Development of Asymmetric Synthesis

Dear Colleagues,

The search for new methodologies leading to the preparation of enantiopure compounds remains extremely active in the field of Organic Synthesis. Thus, the development of new useful asymmetric synthesis approaches results very rewarding, as many therapeutically interesting products are in one enantiomeric form.

Uncountable asymmetric procedures for the synthesis of all kind of compounds have been reported until now, but still plenty of work is necessary to develop convenient, useful, and easily scalable methodologies applicable to the preparation of many structures and also suitable to produce a sufficiently high asymmetric bias. In addition, economic considerations, such as the use of cheap and easily available sources, and, particularly nowadays, environmental considerations, such as the use of safe reagents, catalysts, and solvents, as well as their possible recyclability, are crucial. Therefore, many challenges remain to be confronted.

This Special Issue of Molecules aims to provide a broad overview of the new developments in the use of asymmetric synthesis for the preparation of compounds of interest.

Prof. Rafael Chinchilla
Guest Editor

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