Alkynes: From Reaction Design to Applications in Organic Synthesis
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: closed (30 January 2019) | Viewed by 84871
Special Issue Editor
Interests: organic reaction mechanisms; stereoelectronic effects; organic photochemistry; DNA photocleavage; carbon-rich materials; chemistry of alkynes; radical chemistry; cyclizations; cycloaromatizations; electron upconversion; hole catalysis; high energy functional groups
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alkyne functionality represents one of the most valuable building blocks of organic chemistry. Despite its seeming simplicity, it combines many unusual and attractive features. For example, the compact carbon-rich alkyne moiety stores >60 kcal/mol of potential energy. Furthermore, alkynes have the same oxidation state as carbonyl compounds and, hence, via simple addition of nucleophiles, offer a “hidden door” entry into carbonyl chemistry. Due to the presence of two independently addressable π-systems, alkynes can readily form four (and, under certain conditions, up to six) new bonds, lending themselves perfectly to the design of cascade transformations. The recent examples of unusual alkyne transformations include ionic chemistry of neutral hydrocarbons, preparation of radicals without radical initiators, generation of excited states without light, "1,2-dicarbene reactivity" of alkynes in "boomerang" radical processes, selective conversion of alkynes into carbonyl compounds, and full disassembly of the alkyne moiety. With the advent of modern catalytic methods, it seems that new reactions of alkynes are discovered every day.
Recognizing the hidden connections between the fundamental features of alkynes and their rich reactivity is essential for uncovering the full potential of this functionality in organic synthesis. The goal of this Special Issue to is to bring multiple examples of new alkyne reactions under one cover to catalyze cross-pollination of ideas for the future development of alkyne chemistry. This issue will contain contributions that cover all aspects of alkyne structure, reactivity, and applications in organic synthesis.
Prof. Dr. Igor V. Alabugin
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- alkynes
- cascade transformations
- catalysis
- addition
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.