Special Issue "Enzymes Reacting with Organophosphorus Compounds"
Deadline for manuscript submissions: closed (31 December 2020).
Interests: cholinergic mechanisms in health and neurological disorders; inhibition and reactivation of acetylcholinesterase; enzyme kinetics; antidotes for nerve agents poisoning
It is a great pleasure and honor to invite you to contribute to the Special Issue of Molecules entitled “Enzymes Reacting with Organophosphorus Compounds”. This Special Issue welcomes manuscripts describing original work, as well as review articles on structures, modes of action, and biological roles of enzymes reacting with organophosphorus compounds: acetylcholinesterase, butyrylcholinesterase, paraoxonase, neuropathy target esterases, and other OP hydrolyses. The Guest Editor will be pleased to accept and review manuscripts that address but are not restricted to the topics listed below:
- Advances in research on kinetics and the mechanism of the enzymes action;
- Cholinesterase inactivation by natural and synthetic ligands;
- The reactivation of cholinesterases inhibited by nerve agents and insecticides;
- Structural studies on native enzymes, their complexes with ligands, and their conjugates with organophosphorus compounds;
- Advances in the biology of the enzymes and their cholinergic cross talk and involvement in neurological diseases;
- The regulation and alternative roles of acetylcholinesterases.
Prof. Dr. Zrinka Kovarik
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- OP hydrolase
- Nerve agents
- Cholinergic mechanisms