Special Issue "Recent Advances in CuAAC Click Chemistry"
Deadline for manuscript submissions: closed (30 September 2016)
Prof. Dr. James Crowley
The past decade has seen rapid growth in the number of so-called “click” reactions, synthetic methods that exploit simple reaction conditions, are high yielding, regioselective and readily purified. These click methods have vastly improved our ability to rapidly produce functionalized molecules for applications in the biological and material sciences.
Of the “click” technologies available, the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) remains the go-to reaction due to the functional group tolerance of the process. Initially, the CuAAC reaction was mainly exploited to conjugate two components together in high yield through a 1,4-disubstituted 1,2,3-triazole unit. However, more recently it has been shown that the 1,2,3-triazole units generated via the CuAAC reaction can engage in hydrogen bonding and metal coordination further widening the interest in this “click” reaction.
This Special Issue of Molecules will seek to highlight the continuing growth in the use of CuAAC “click” chemistry in a range of areas including catalysis, coordination, medicinal and supramolecular chemistry, biology, material science and nanotechnology. I strongly encourage colleagues to submit their manuscript for this Special Issue, which will promote and celebrate the applications of this powerful synthetic technology.
Prof. Dr. James Crowley
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- click chemistry
- chemical ligation
- medicinal chemistry
- supramolecular chemistry
- coordination chemistry
- material science