Next-Generation Molecular Diagnostics: Mass Spectrometry-Based Omics Insights into Complex Disease Architectures
A Special Issue of Molecules (ISSN 1420-3049) belonging to the section "Analytical Chemistry".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 660
Editors
Interests: purification and characterization of enzymes and structural proteins; investigation of the proteome of different tissues/fluids by using the conventional methods of proteomics/metabolomics
Special Issues, Collections and Topics in MDPI journals
Interests: mass spectrometry; proteomics; molecular diagnostics; biomarkers; chronic obstructive lung diseases; alpha1-antitrypsin deficiency
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Advances in high-throughput technologies are reshaping our ability to detect, classify, and understand complex diseases at unprecedented resolution. This Special Issue focuses on next‑generation molecular diagnostics driven by different omics approaches, including proteomics, metabolomics, and other integrated analytical strategies based on mass spectrometry and related technologies. By combining diverse molecular layers, different omics profiling offers deeper mechanistic insights into disease onset, progression, heterogeneity, and therapeutic response.
We invite contributions that highlight innovative analytical methods, novel diagnostic biomarkers, cutting‑edge proteomic and metabolomic workflows, and integrative computational models that improve disease prediction and individualized treatment. Studies involving experimental, computational, or translational perspectives are welcome.
This Special Issue aims to showcase the latest advances that bridge molecular science and clinical application, accelerating the development of precise, reliable, and early diagnostic tools for complex diseases.
Prof. Dr. Paolo Iadarola
Dr. Simona Viglio
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- proteomics
- metabolomics
- mass spectrometry-based
- molecular diagnostics
- biomarkers
- disease heterogeneity
- systems biology
- precision medicine
- integrative analysis
- complex diseases
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