Cyclization Reactions in Organic Synthesis: Recent Developments

Dear Colleagues,

Cyclization reactions are a powerful tool in organic synthesis for the construction of cyclic compounds, which present a wide variety of applications in several areas, such as drug discovery, agrochemicals, and materials science.

One of the most significant advantages of these transformations is the ability to generate molecular complexity with high stereochemical control, a crucial feature in the synthesis of natural products and in the pharmaceutical industry. Additionally, these processes enable the synthesis of complex structures with specific ring sizes and shapes, including strained rings, which are difficult to obtain otherwise. Moreover, they often require fewer steps and reagents compared to the classical synthetic methods, resulting in less waste generation and a reduction in the environmental impact, in line with the principles of green chemistry.

In recent decades, cyclization reactions have become increasingly important in organic synthesis and have contributed to the development of novel bioactive compounds, agrochemicals, and polymers, as well as new synthetic routes to natural products.

This Special Issue, “Cyclization Reactions in Organic Synthesis: Recent Developments”, aims to gather the most recent advances on this topic. Full papers, communications, and reviews are all welcome for submission.

Dr. Ana L. Cardoso
Dr. Maria Isabel L. Soares
Guest Editors

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