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Special Issue "Microfluidic Platforms for Cell Culture and Investigations"
A special issue of Micromachines (ISSN 2072-666X).
Deadline for manuscript submissions: 1 December 2019.
Interests: mobile cell culture systems; on-chip reconstruction of vascular remodeling; cell-free DNA isolation
A cell culture is the result of a collection of techniques for isolating cells from animals or plants and maintaining them in apparatus, instead of using them at their origin. The aim of the cell culture is to control the fluidic, physicochemical, nutritional, scaffold, and other biological requirements for their survival, proliferation, and desired differentiation. Recent advances in microtechnology and tissue engineering have extended the cell culture to a wider range of cell numbers and densities, from single cells to 3D co-cultures, and for a wider range of cell culture cycles, from quick disposable cultures to very-long-term cell cultures. Microfluidic technology has also enabled the integration of various cell culture techniques into a chip, i.e., towards the realization of miniaturized cell-processing systems.
This Special Issue aims to turn the spotlight on microsystems for advanced cell culture. Numerous microfluidic systems for various cell-based assays are already the subject of intensive research, including on-chip cellomics and organ-on-chip, as already covered in other Special Issues in Micromachines. This Special Issue rather focuses on the concepts, devices, and methods for enhanced cell culture, including but not limited to fluidic/temperature/gas level control methods, cell handling such as sorting and preservation, and monitoring of cell culture media, all of which constitute the fundamentals of on-chip cellular assays and processing. In addition, this Special Issue will cover simple and effective microfluidic methods that address physicochemical instability and/or high adoption, and the learning costs that inherently come from microtechnology-origin cell culture systems. Downsizing and improving the traditional cell culture techniques will also open new possibilities in portable and affordable cell processing and cell-based sensing systems that will greatly contribute to precision medicine and accurate environmental monitoring.
Prof. Dr. Nobuyuki Futai
Dr. Atsushi Takano
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Long-Term Culture
- Hypoxic/Hyperoxic Culture
- Culture in Gradients
- Coculture/3D Culture
- Single-Cell Culture
- On-Chip Cell Sorting/Harvesting/Passaging
- On-Chip Culture for Environment Monitoring