Special Issue "Current Progress in Prion Research"
A special issue of Microbiology Research (ISSN 2036-7481).
Deadline for manuscript submissions: 30 September 2023 | Viewed by 495
Although accumulating but conflicting reports have discussed the possible roles of prion protein (PrP) in Alzheimer’s disease (AD), whether and how prion interacts with β-amyloid precursor protein (APP) and/or microtubule-associated protein tau (Mapt) remains elusive. This Special Issue collects evidence regarding the interaction of prion with APP, β-amyloid (Aβ) and/or tau. PrPC may influence APP amyloidogenic pathways and exosome-related Aβ secretion. Prion may also affect autophagy by regulating levels of dephosphorylated Tau. Therefore, prion may be important in the development of AD.
Dr. Kefeng Qin
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- prion diseases
- protein structure
- Alzheimer’s disease