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Microbiology Research
Special Issues
Current Progress in Prion Research
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Special Issue "Current Progress in Prion Research"

A special issue of Microbiology Research (ISSN 2036-7481).

Deadline for manuscript submissions: 30 September 2023 | Viewed by 495

Special Issue Editor

Dr. Kefeng Qin
E-Mail Website
Guest Editor
Department of Neurology, University of Chicago, Chicago, IL, USA
Interests: prion; protein structure; copper; Alzheimer’s disease

Special Issue Information

Dear Colleagues,

Although accumulating but conflicting reports have discussed the possible roles of prion protein (PrP) in Alzheimer’s disease (AD), whether and how prion interacts with β-amyloid precursor protein (APP) and/or microtubule-associated protein tau (Mapt) remains elusive. This Special Issue collects evidence regarding the interaction of prion with APP, β-amyloid (Aβ) and/or tau. PrPC may influence APP amyloidogenic pathways and exosome-related Aβ secretion. Prion may also affect autophagy by regulating levels of dephosphorylated Tau. Therefore, prion may be important in the development of AD.

Dr. Kefeng Qin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microbiology Research is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prion
  • prion diseases
  • protein structure
  • Alzheimer’s disease

Published Papers (1 paper)

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Review
Clustering Disease of Clostridioides Difficile Infection: Implication for the Management in Internal Medicine
by
Pietro Crispino
Microbiol. Res. 2023, 14(3), 1376-1397; https://doi.org/10.3390/microbiolres14030094 - 15 Sep 2023
Viewed by 319
Abstract
Clostridioides difficile is a bacterium responsible for a healthcare-associated gastrointestinal infection, primarily affecting people who have undergone prolonged antibiotic treatment or who have compromised immune systems. The CD is of particular concern due to its high recurrence rates and the potential for serious [...] Read more.
Clostridioides difficile is a bacterium responsible for a healthcare-associated gastrointestinal infection, primarily affecting people who have undergone prolonged antibiotic treatment or who have compromised immune systems. The CD is of particular concern due to its high recurrence rates and the potential for serious outcomes, including life-threatening conditions such as pseudomembranous colitis, septic shock, and all associated conditions. Since this infection is a disease associated with other health conditions, a general vision of the problems is necessary which aims to obtain a general overview of the manifestations that generally correlate with care. Clinical reasoning following the disease-clustering method is able to produce a categorization process by grouping the possible correlations of the various conditions or factors underlying diseases on the basis of certain similarities or common models. The clustering process is performed using data analysis techniques which, by statically correlating each other, give an exact dimension of all the information related to a particular disease. In the case of CD, reasoning based on disease clustering has better clarified the practices, appropriateness in infection control, judicious use of antibiotics, and research into therapeutic and preventive strategies. This review, taking advantage of the clustering strategy, aimed to analyze the contingent conditions of the infection under examination, to reduce the incidence and impact of CD, having as its mission the improvement of the results deriving from the contrast of all those correlated pathological conditions to healthcare for the improvement of public health. Full article
(This article belongs to the Special Issue Current Progress in Prion Research)
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