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Microbiology Research, Volume 16, Issue 11

2025 November - 22 articles

Cover Story: Wheat is a global staple crop, sustaining food security for billions. Understanding how it defends itself against major pathogens is essential for protecting yield and ensuring long-term resilience. In this study, we used RNA-seq and weighted gene co-expression network analysis to uncover coordinated molecular responses to the Tan Spot pathogen Pyrenophora tritici-repentis. By comparing resistant and susceptible cultivars, we identified distinct defense signatures and novel hub genes linked to resistance or susceptibility. We also found common pathogen-triggered responses shared by both wheat lines. These findings reveal previously uncharacterized components of wheat immunity and provide candidates for improving disease-resistant varieties. View this paper
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Articles (22)

  • Case Report
  • Open Access
1,251 Views
12 Pages

Pulmonary Cryptococcosis in a Diabetic Patient Without Severe Immunosuppression: Case Report and 25-Year Literature Review

  • Suyapa Sosa,
  • María Fernanda Manzanares,
  • Daniel Rivera,
  • Asly Villeda-Barahona,
  • Gustavo Fontecha,
  • Yaxsier de Armas and
  • Bryan Ortiz

Pulmonary cryptococcosis is an invasive fungal infection usually linked to severe immunosuppression, particularly HIV/AIDS, but is increasingly reported in immunocompetent hosts, including those with uncontrolled diabetes mellitus (DM). We describe a...

  • Systematic Review
  • Open Access
1,350 Views
17 Pages

Association Between Gut Microbiome Alterations and Hypertension-Related Cardiovascular Outcomes: A Systematic Review and Meta-Analysis

  • Adina-Cristiana Avram,
  • Maria-Laura Craciun,
  • Ana-Maria Pah,
  • Florina Buleu,
  • Ioana-Georgiana Cotet,
  • Diana-Maria Mateescu,
  • Stela Iurciuc,
  • Simina Crisan,
  • Oana Belei and
  • Claudiu Avram
  • + 1 author

Hypertension (HTN) remains a major modifiable risk factor for cardiovascular disease (CVD), yet the mechanisms linking environmental and metabolic factors to vascular injury are incompletely understood. Recent evidence implicates gut microbiome dysbi...

  • Communication
  • Open Access
538 Views
9 Pages

Development of a Sensitive and Selective Fluorescent Substrate for the Detection of Chitinase Activity in Entomopathogenic Fungi

  • Estefan Miranda-Miranda,
  • César A. Arreguín-Pérez,
  • Hugo Aguilar-Díaz and
  • Raquel Cossío-Bayúgar

The identification and quantification of chitinolytic activity in microorganisms is critical for advancing biological control strategies against arthropod pests and fungal pathogens. However, current laboratory methods designed for fast detection of...

  • Article
  • Open Access
1 Citations
753 Views
23 Pages

Molecular Networks Underlying Wheat Resistance and Susceptibility to Pyrenophora tritici-repentis

  • Larissa Carvalho Ferreira,
  • Flavio Martins Santana and
  • Luis A. J. Mur

Pyrenophora tritici-repentis (Ptr), the causal agent of tan spot, is a necrotrophic fungus that represents a significant threat to wheat production worldwide. The development of resistant cultivars is limited by an incomplete understanding of wheat d...

  • Review
  • Open Access
3,043 Views
25 Pages

The gut microbiome is essential for nutrient absorption, immune function, and overall metabolic health. A balanced microbial community allows for the breakdown of carbohydrates, proteins, fats, vitamins, and minerals into maximally absorbed nutrients...

  • Article
  • Open Access
1,911 Views
10 Pages

Urinary tract infections (UTIs) are a global health concern, with over 150 million cases annually, primarily caused by Escherichia coli. Due to anatomical differences, females, especially children and postmenopausal women, are four times more suscept...

  • Article
  • Open Access
581 Views
18 Pages

Sensitive Detection of β-Carotene in Chromogenic and Non-Chromogenic Mycobacteria by HPLC-DAD and UHPLC-MS

  • Ana Milena Murillo,
  • Juan David Zapata Serna,
  • Verónica Gómez Tangarife,
  • Jaime Alberto Robledo Restrepo and
  • Luz Elena Botero

Carotenoid pigments are widely distributed in nature and play a crucial role in protecting organisms from photodynamic damage. However, the characterization of carotenoid production in clinically relevant mycobacteria has been limited due to the low...

  • Article
  • Open Access
840 Views
17 Pages

Methanolic Extract of Moringa oleifera Seed Synergizes the Bactericidal Effect of Ampicillin, Cephalexin, and Amoxicillin/Clavulanic Acid Against Multidrug-Resistant Escherichia coli Isolated from Street-Vended Food

  • Daniela Mora-Coto,
  • Pedro R. Moreno-Vélez,
  • José Luna-Muñoz,
  • José Jaime Jarero-Basulto,
  • Anahi Pérez-Galicia,
  • Samadhi Moreno-Campuzano and
  • Miguel Angel Ontiveros-Torres

Background: Antibiotic drug resistance is a serious global health problem that threatens therapeutics against infectious diseases. As antibiotics become less effective every year, our objective was to evaluate the adjuvant activity of methanolic extr...

  • Article
  • Open Access
604 Views
17 Pages

Exploration and Comparison of High-Throughput Sequencing Analysis of Endophytic Fungal Communities in Morinda tinctoria and Pithecellobium dulce

  • Michael Joe Xavier Sneha,
  • Israel Mani,
  • Myithili Thangavel,
  • Senthuran Suresh Kumar,
  • Pandy Rajapriya,
  • Nagendraprabhu Ponnuraj and
  • Mohan Pandi

Fungal endophytes can be identified in a wide range of plant species which help to protect from both abiotic and biotic stressors. This research focused on using high-throughput sequencing (HTS) analysis to gain insight into the foliar endophytic fun...

  • Article
  • Open Access
790 Views
20 Pages

Vimentin Methylation as a Potential Screening Biomarker for Colorectal Cancer in HIV-Helminth Co-Infected Individuals

  • Botle Precious Damane,
  • Shakeel Kader,
  • Mohammed Alaouna,
  • Pragalathan Naidoo,
  • Zodwa Dlamini and
  • Zilungile Lynette Mkhize-Kwitshana

Colonoscopy remains the gold standard for colorectal cancer (CRC) screening, but its invasiveness, cost, and limited availability in resource-constrained settings pose major barriers. Stool-based methylated DNA biomarkers, such as vimentin, offer sen...

  • Article
  • Open Access
512 Views
11 Pages

Crown gall disease, caused by soil-borne bacterial pathogens, such as Allorhizobium vitis, poses a significant threat to grapevine cultivation in Japan, particularly under environmental conditions exacerbated by climate change. Effective chemical con...

  • Communication
  • Open Access
2,534 Views
10 Pages

Field emission scanning electron microscopy (FE-SEM) may be used to visualize the surface morphology of samples that are permeable to electron beams, including biological samples. Probiotics attenuate host physiological functions and are characterize...

  • Review
  • Open Access
1,160 Views
23 Pages

Venomous snakes constitute ecologically significant and medically relevant organisms due to the risks associated with their bites, which frequently result in secondary infections. The oral microbiota of these reptiles plays a crucial role in the path...

  • Article
  • Open Access
1,935 Views
11 Pages

Helicobacter pylori is a gastric pathogen that induces chronic gastritis, which may progress to neutrophilic activity, glandular atrophy, intestinal metaplasia, and gastric carcinoma. The aim of this study was to evaluate H. pylori-induced tissue dam...

  • Article
  • Open Access
1,095 Views
15 Pages

Diversity and Antimicrobial Resistance of Staphylococci Isolated from Healthy Dogs and Cats in Southern Brazil

  • Letícia da Silva,
  • Tamiris Silva Lopes,
  • Gustavo Brambatti,
  • Aline de Barros Moyses,
  • Leandro do Monte Ribas,
  • Diéssy Kipper,
  • André Felipe Streck and
  • Vagner Ricardo Lunge

Staphylococcus spp. are potential pathogens classified into more than 50 species, frequently presenting antimicrobial resistance (AMR) to several drugs. The present study aimed to identify the Staphylococcus species and their AMR in staphylococci iso...

  • Article
  • Open Access
822 Views
16 Pages

Sapindus mukorrosi (Sm) seeds have been used in Chinese medicine for treating gingival disease, suggesting that Sm may modulate oral bacteria and alleviate gingival inflammation. However, the hydrophobicity of seed oil limits its use in the aqueous o...

  • Article
  • Open Access
976 Views
13 Pages

Microbial and Chemical Contamination in Springs of Northern and Central Lithuania

  • Žaneta Maželienė,
  • Giedrė Jarienė and
  • Asta Aleksandravičienė

Groundwater springs are an important source of drinking water in Lithuania; however, they are highly sensitive to microbial and chemical contamination. The aim of this study was to assess microbial and chemical contamination in springs from different...

  • Communication
  • Open Access
1,098 Views
12 Pages

Efficacy of an Indigenously Isolated Rice Field Methanotroph as a Potential Bio-Inoculant for Promoting Rice Plant Growth

  • Shubha Manvi,
  • Kajal Pardhi,
  • Shirish Kadam,
  • Yash Kadam,
  • Yukta Patil,
  • Rahul A. Bahulikar and
  • Monali C. Rahalkar

Methanotrophs offer promising avenues for sustainable agriculture and climate mitigation. This study evaluates the efficacy of indigenously isolated methanotrophs, particularly Methylomonas Kb3, as bioinoculants in rice cultivation. Kb3-treated plant...

  • Article
  • Open Access
1 Citations
1,049 Views
25 Pages

Ion Homeostasis, Osmotic Adjustment, and ROS Detoxification Underlie Pea Salinity Tolerance Induced by Pseudomonas putida RT12

  • Amir Abdullah Khan,
  • Khulood Fahad Alabbosh,
  • Kashif,
  • Babar Iqbal,
  • Sehrish Manan,
  • Wardah A. Alhoqail,
  • Dao-Lin Du and
  • Yong-Feng Wang

In saline soil, legumes are restricted in their growth potential by osmotic stress, ion toxicity, and oxidative damage. We evaluated five halotolerant plant growth-promoting bacteria and selected Pseudomonas putida RT12 for its exceptional EPS produc...

  • Review
  • Open Access
1,906 Views
20 Pages

The Growing Antibiotic Resistance of Campylobacter Species: Is There Any Link with Climate Change?

  • Eleni V. Geladari,
  • Dimitris Kounatidis,
  • Evangelia Margellou,
  • Apostolos Evangelopoulos,
  • Edison Jahaj,
  • Andreas Adamou,
  • Vassilios Sevastianos,
  • Charalampia V. Geladari and
  • Natalia G. Vallianou

Campylobacter spp. remain among the most common pathogens causing acute diarrhea worldwide. Campylobacter jejuni and Campylobacter coli are the main species that cause gastroenteritis. Campylobacteriosis is a food-borne disease, although this Gram-ne...

  • Article
  • Open Access
1,190 Views
15 Pages

Isolation and Characterization of Microorganism Associated with Vanilla planifolia Produced in Different Production Systems in México

  • Dannia Fernanda Garrido-Fernández,
  • Lorena Jaqueline Gómez-Godínez,
  • Delfino Reyes-López,
  • Carlos Hugo Avendaño-Arrazate,
  • Ramón Ignacio Arteaga-Garibay,
  • José Martín Ruvalcaba-Gómez,
  • Carmela Hernández-Dominguez and
  • Fernando López-Morales

The microbiota associated with Vanilla planifolia grown in three production systems in Puebla, México, was evaluated: shade cloth, cocuite, and acahual. Rhizosphere and soil samples were analyzed, from which bacteria, fungi, yeasts, and actino...

  • Article
  • Open Access
870 Views
17 Pages

The genus Diaporthe consists of saprobes, endophytes, and important plant pathogens. Members of this genus are widely distributed and have a broad host range, including grapevines. This study aimed to establish a baseline survey to assess the diversi...

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Microbiol. Res. - ISSN 2036-7481