Structure and Properties of Biomedical Alloys

Dear Colleagues,

Biomedical alloys continue to play a central role in the development of next-generation medical implants and devices. The rapid growth of additive manufacturing, advanced thermomechanical processing, and surface-engineering technologies has enabled unprecedented control over microstructure, defect population, and interfaces in metallic biomaterials. These advances have accelerated the transition from conventional alloys to highly tailored compositions and architectures designed to improve biocompatibility, corrosion behavior, mechanical reliability, and long-term clinical performance. At the same time, the study of structure–property relationships—particularly at multiple length scales—remains essential for understanding how processing routes ultimately govern biological response and functional outcomes.

Within this context, the field is experiencing a surge of innovation, driven by emerging biomedical needs such as low-modulus implants, antibacterial surfaces, controlled degradation, and enhanced osseointegration. Novel alloys based on Ti, Mg, Co–Cr, and high-entropy systems, together with gradient and porous structures, are rapidly reshaping the landscape of metallic biomaterials. Insights from advanced characterization techniques, in situ mechanical testing, and multiscale modeling are also contributing to a deeper understanding of how microstructural evolution affects performance in physiological environments.

For this Special Issue, we welcome articles that focus on material preparation methods and their influence on the performance of final products, in both the powder stage and compaction domain. Fully controllable, fast, and low-cost processes are also of interest, specifically those with high implementation potential in advanced powder technologies that allow production of high-performance products.

Of particular interest are contributions dealing with the structure and properties of biomedical alloys, including processing–microstructure–performance relationships, corrosion and wear behavior, mechanical and biological performance, design of porous or architected structures, and surface or interface modifications. Submissions addressing emerging alloy systems, innovative characterization approaches, and structure-driven strategies to improve clinical functionality are especially encouraged.

Dr. Sheila Lascano
Dr. Cristina Arevalo Mora
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomedical alloys
• microstructure–property relationships
• additive manufacturing of biomaterials
• titanium-based alloys
• magnesium biodegradable alloys
• cobalt–chromium alloys
• high-entropy alloys for biomedical applications
• surface modification and biofunctionality
• corrosion and wear behavior in physiological environments
• biocompatibility and cytotoxicity evaluation