Prostaglandin Metabolites

Dear colleagues,

Prostaglandins are bioactive signaling lipids involved in different biological activities and diseases, and the discovery of these compounds was awarded the Nobel Prize for Physiology or Medicine in 1982, highlighting their importance. These compounds are unstable, and many downstream metabolites have been shown to have additional functions and be involved in feedback mechanisms. Important research regarding prostaglandin metabolites has been carried out in various fields, but consensus has not always been reached, and several questions remain to be answered. What known and novel metabolites can be detected in a certain tissue and what type of functions do they have under a certain condition, in a certain cell type, and in a certain species? Do specific metabolites have different functions in different diseases, and what is the common profile of metabolites? Do the metabolites originate from local production or systemic biosynthesis? Can prostaglandin metabolites be used as biomarkers for disease progression and response to treatment? By combining scientific work performed within different disciplines with focus on prostaglandin metabolites, knowledge in metabolite functions will be enhanced and facilitated by this Special Issue.

This Special Issue welcomes the submission of papers describing biosynthesis, characterization, and function of prostaglandin metabolites. Clinical applications and biomarker studies performed on these metabolites are of great interest, as well as methodological improvement for detection of prostaglandin metabolites. Knowledge in the interaction between different eicosanoids and their functions in comparable models are relevant and studies on other metabolites in the arachidonic acid cascade might also be taken into consideration for publication in this issue.

Dr. Helena Idborg
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.