Challenges and Opportunities in Application of Mass Spectrometry for Metabolomics and Lipidomics

Dear Colleagues,

We are pleased to announce the Special Issue titled "Challenges and Opportunities in Mass-Spectrometry-Based Metabolomics and Lipidomics", aiming to highlight new scientific applications in mass spectrometry-based metabolomics and lipidomics and address the associated challenges.

Metabolomics is an interdisciplinary field that brings together experts from various disciplines such as analytical chemistry, biochemistry, statistics, biology, computational science and medicine. Among the various analytical platforms available, mass spectrometry stands out as a primary tool for exploring the metabolome due to its high sensitivity and specificity in chemical analyses. It is often used in conjunction with separation techniques such as gas or liquid chromatography—and more recently ion mobility—to improve the analysis of complex samples.

While significant progress has been made in the metabolomics and lipidomics fields, several challenges remain. These include the annotation of metabolites in discovery-based studies, the validation of proposed biomarkers, the development of user-friendly visualization methods for interpreting multivariate analysis outputs, the standardization of large data processing workflows, the achievement of consistent results in inter-laboratory comparisons and the translation of findings into clinical settings.

We encourage researchers to submit their work to this Special Issue covering original research and review articles which address analytical challenges, new advances, and recent applications in mass-spectrometry-based metabolomics and lipidomics.

Dr. Konstantinos Kouremenos
Dr. David J. Beale
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.