Advances in Laparoscopic Surgery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: 20 November 2026 | Viewed by 3272

Special Issue Editors


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Guest Editor
Department of Public Health, School of Medicine, University of Naples “Federico II”, 80131 Naples, Italy
Interests: gynecologic oncology; benign gynecological pathology; endometriosis; minimally invasive surgery; advanced gynecological ultrasound; cervico-vaginal pathology; colposcopy; hysteroscopy; gynecological endocrinology and metabolic disorders

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Guest Editor
Gynecology and Obstetrics Unit, Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy
Interests: oncological gynecology; ovarian cancer; vulvar cancer; endometriosis; PCOS
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Special Issue Information

Dear Colleagues,

Over the past few decades, laparoscopic surgery has transformed from a diagnostic tool to the cornerstone of modern minimally invasive treatment across various surgical specialties. In gynecology, general surgery, and urology alike, laparoscopy has significantly reduced postoperative morbidity, hospital stay, and recovery time, while improving surgical precision. With continuous innovation in instrumentation, imaging technologies, and surgical training, laparoscopic techniques are now applied to increasingly complex cases that once required open surgery.

This Special Issue aims to provide a comprehensive overview of recent advances in laparoscopic surgery, spanning technical innovations, novel clinical applications, training models, and outcome-based research. We seek to highlight how cutting-edge laparoscopy is improving patient care, reshaping surgical education, and contributing to personalized surgical strategies. Special attention will also be given to hybrid approaches combining laparoscopy or robotic surgery with other minimally invasive modalities, such as hysteroscopy or intraoperative ultrasound, which are gaining ground in complex surgical planning and execution.

In particular, we will focus on laparoscopic approaches applied to gynecological diseases, including both benign conditions—such as endometriosis and uterine fibroids—and oncological pathologies, where minimally invasive surgery is increasingly being adopted as the standard of care. Contributions dealing with the laparoscopic management of complex pelvic anatomy, fertility-sparing procedures, or oncologic staging are highly encouraged.

The issue will focus on state-of-the-art technologies such as 3D and robotic-assisted laparoscopy, fluorescence-guided surgery, augmented reality, artificial intelligence integration, and enhanced recovery protocols. Additionally, we welcome contributions exploring synergistic techniques that integrate endoscopic approaches—such as hysteroscopy or intraoperative ultrasound—with laparoscopic or robotic platforms to enhance surgical accuracy and safety, particularly in challenging anatomical scenarios. Research evaluating clinical outcomes, learning curves, and cost-effectiveness of such strategies is especially valued.

We invite high-quality original research articles, systematic reviews, meta-analyses, narrative reviews, and technical notes that address any aspect of laparoscopic surgery. Manuscripts reporting on new surgical techniques, training methodologies, hybrid procedures, patient-centered outcomes, or comparative studies between laparoscopic and other surgical approaches are particularly encouraged. Submissions across all surgical disciplines are welcome, with a dedicated interest in gynecological applications—both benign and malignant—that advance the role of laparoscopy in modern surgical practice.

Dr. Mario Palumbo
Dr. Luigi Della Corte
Guest Editors

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Keywords

  • laparoscopic surgery
  • minimally invasive gynecology
  • robotic-assisted surgery intraoperative ultrasound
  • hysteroscopy
  • gynecologic oncology
  • endometriosis
  • benign gynecology

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Published Papers (2 papers)

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12 pages, 530 KB  
Article
Simultaneous TEP Inguinal Hernia Repair and Laparoscopic Cholecystectomy: A Retrospective Analysis of Safety, Cost-Effectiveness, and Outcomes
by Zekai Serhan Derici, Berke Manoğlu, Tayfun Bişgin, Cihan Ağalar, Mert Kazancı, Tufan Egeli and Süleyman Özkan Aksoy
Medicina 2026, 62(2), 330; https://doi.org/10.3390/medicina62020330 - 6 Feb 2026
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Abstract
Background and Objectives: The concurrent management of cholelithiasis and inguinal hernia remains a subject of surgical debate, primarily due to concerns regarding prosthetic mesh infection in a clean-contaminated field. This study evaluates the safety, cost-effectiveness, and functional outcomes of simultaneous totally extraperitoneal [...] Read more.
Background and Objectives: The concurrent management of cholelithiasis and inguinal hernia remains a subject of surgical debate, primarily due to concerns regarding prosthetic mesh infection in a clean-contaminated field. This study evaluates the safety, cost-effectiveness, and functional outcomes of simultaneous totally extraperitoneal (TEP) repair and laparoscopic cholecystectomy (LC). Materials and Methods: A retrospective analysis was conducted on patients treated between 2015 and 2025 using a prospectively maintained institutional registry. The cohort was stratified into two arms: the Simultaneous Group (n = 16), undergoing synchronous TEP and LC; and the Staged Group (n = 13), managed via separate sessions. A strict “hernia-first” operative sequence was enforced to maintain sterility. Key endpoints included perioperative morbidity, long-term recurrence (mean follow-up: 53.9 months), economic burden, and quality of life (EuraHS-QoL). Results: No surgical site or prosthetic infections were documented in either cohort. The Simultaneous arm demonstrated a significantly reduced total operative duration compared to the cumulative time of the Staged approach (164.6 ± 44.9 vs. 226.2 ± 57.4 min; p = 0.003) and yielded a shorter hospitalization period (1.44 ± 0.51 vs. 2.31 ± 0.85 days; p = 0.002). Workforce reintegration was markedly accelerated in the simultaneous group (9.43 ± 3.36 vs. 24.69 ± 12.35 days; p < 0.001), translating to a total cost reduction of approximately 51% for unilateral cases. Conclusions: Concomitant TEP and LC represents a clinically viable and financially prudent strategy that does not compromise patient safety or prosthetic durability. Adherence to a strict “hernia-first” surgical sequence appears critical to preventing infectious morbidity. Given the superior resource utilization, this dual approach merits consideration as a primary therapeutic algorithm. Full article
(This article belongs to the Special Issue Advances in Laparoscopic Surgery)
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31 pages, 992 KB  
Systematic Review
Tubal Stump Ectopic Pregnancy After IVF-ET in Patients Who Underwent Salpingectomy or Adnexectomy: A Qualitative Systematic Review
by Massimo Criscione, Giorgio Maria Baldini, Elisa Sanna, Laura Saderi, Giovanni Sotgiu, Mario Palumbo, Marco Petrillo and Giampiero Capobianco
Medicina 2026, 62(1), 83; https://doi.org/10.3390/medicina62010083 - 31 Dec 2025
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Abstract
Background and Objectives: Ectopic pregnancy (EP) is a life-threatening medical and surgical condition. Tubal stump EPs and heterotopic pregnancies can occur after in vitro fertilization-embryo transfer (IVF-ET), even after salpingectomy. The purpose of this study is to investigate the risk factors, diagnosis, and [...] Read more.
Background and Objectives: Ectopic pregnancy (EP) is a life-threatening medical and surgical condition. Tubal stump EPs and heterotopic pregnancies can occur after in vitro fertilization-embryo transfer (IVF-ET), even after salpingectomy. The purpose of this study is to investigate the risk factors, diagnosis, and treatment of tubal stump EPs after IVF-ET in patients with prior salpingectomy or adnexectomy. We also aim to evaluate the intrauterine pregnancy (IUP) outcome in cases of heterotopic pregnancy in this population. Materials and Methods: This systematic review (PROSPERO CRD42023352959) followed PRISMA guidelines. A literature search of MEDLINE®, Scopus, Web of Science, and clinicaltrials.gov was conducted on 30 April 2024. We included studies on tubal stump EP after IVF-ET in patients with previous salpingectomy or adnexectomy and created a qualitative summary. Results: We included 40 studies reporting on 57 patients (58 EP episodes). Most patients (69.0%) had prior bilateral salpingectomy. Tubal rupture occurred in 69.6% of cases, with 69.0% of these cases reporting hemoperitoneum. Abdominal pain was the most frequent symptom (71.7%). Heterotopic pregnancy occurred in 60.0% of cases (82.7% singletons). The IUP outcome was delivery in 81.9% of cases, with 95.5% of singletons delivering at term, compared with 40.0% of twins. The surgical approach (laparoscopy vs. laparotomy) did not change the IUP outcome. Tubal stump excision (74.1%) was the most common treatment. Overall, the certainty of the evidence was judged as moderate to very low according to the GRADE-CERQual approach, mainly due to small sample sizes, observational designs, and heterogeneity among studies. Conclusions: This review, the first on this topic, provides key data for counselling patients with a tubal stump heterotopic pregnancy. Despite its rarity, close follow-up until 8–10 weeks is recommended for IVF-ET patients with positive β-hCG, monitoring for abdominal pain. Successful management (expectant, medical, or surgical) should be guided by β-hCG levels and ultrasound findings (e.g., absence of heartbeat). Medical treatment shows encouraging obstetric outcomes and warrants further research. Full article
(This article belongs to the Special Issue Advances in Laparoscopic Surgery)
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