Special Issue "New Challenges in Structure Elucidation of Marine Natural Products: NMR Analyses and Other Advanced Methods"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (31 May 2020).
Interests: marine natural product chemistry; marine sponges; marine microbiology; marine chemical ecology; bioactivity
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Special Issue in Marine Drugs: Taking On the Challenges of Marine Natural Products Structure Elucidation
The marine field continues to represent a prolific source of innovative natural products with remarkable biological activities. However, the structure elucidation of these specialized metabolites is often a true challenge due to their small quantity and their complexity. Most of the isolated molecules possess multiple stereocenters, can be halogenated or have peculiar functional groups. Assigning the absolute stereostructure and the conformational properties, which are crucial in biological activities, remains a challenging problem.
X-Ray analyses for crystalline compounds or chemical synthesis approaches including chemical degradation as well as NMR chiral derivatization but also computational studies are the main strategies developed for elucidating the absolute configuration of these molecules. More recently, original approaches of chiroptical methods such as electronic circular dichroism and vibrational circular dichroism have emerged as powerful tools expanding the traditional methods.
This Special Issue proposes to focus on the different challenging strategies, including advanced NMR and innovative stereochemistry determination approaches, for solving the identification of the marine natural products.
Dr. Marie-Lise Bourguet-Kondracki
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- NMR analyses
- X-ray structure analyses
- partial or total enantioselective synthesis
- chemical degradation
- NMR analyses of Mosher esters and related derivatives
- electronic circular dichroism (ECD or CD)
- vibrational circular dichroism (VCD)