Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 10 Oct 2025 | Viewed by 330 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Exploiting Metabolic Weaknesses: A Novel Approach to Overcome Drug Resistance in Cancer Therapy
edited by
submission deadline 15 Oct 2025 | 1 articles | Viewed by 3722 | Submission Open
Keywords: drug resistance; tumor metabolism; immunometabolism; metabolomics; metabolites; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Dermatology: Molecular Mechanisms, Diagnosis and Therapeutic Targets submission deadline 15 Oct 2025 | 2 articles | Viewed by 3708 | Submission Open
Keywords: dermatologic diseases; atopic dermatitis; psoriasis; hidradenitis suppurativa; vitiligo; alopecia; melanoma; scleroderma
(This special issue belongs to the Section Molecular Targeted Therapy)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 15 Oct 2025 | 1 articles | Viewed by 1174 | Submission Open
Keywords: artificial intelligence  ; personalized medicine  ; predictive modeling  ; genomics  ; proteomics  ; AI-driven diagnostics  ; patient-specific treatment  ; drug discovery  ; healthcare innovation  ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Multiple Biomarkers for the Diagnosis and Precision Treatment of Depression
edited by
submission deadline 15 Oct 2025 | Viewed by 533 | Submission Open
Keywords: depression; biomarkers; inflammation; autoimmunity; genomics; physiology; radiography
(This special issue belongs to the Section Disease Biomarkers)
Personalized Medicine in Otolaryngology: Novel Prognostic Markers
edited by and Wolf-Dieter Baumgartner
submission deadline 20 Oct 2025 | 5 articles | Viewed by 10634 | Submission Open
Keywords: personalized medicine; otorhinolaryngology; otology; head and neck surgery; prognostic markers; individualized treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Hearing Disorder: Diagnosis, Implantation and Latest Research submission deadline 20 Oct 2025 | 1 articles | Viewed by 4515 | Submission Open
Keywords: hearing loss; cochlear implants; hearing preservation; neuroplasticity; outcomes in cochlear implantation; prosthesis fitting; bone-anchored hearing aids; speech perception; sound localization; gene therapy; inner-ear cell regeneration; vestibular disorders; telemedicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Hepato-Pancreatic-Biliary Surgery: New Perspectives in Precision Medicine Era
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 2043 | Submission Open
Keywords: hepato-pancreatic– biliary surgery; precision medicine; genomics; proteomics; nanotechnologies; molecular pathways; artificial intelligence; predictive modeling
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Cancer Biology and Precision Oncology
edited by Wen-Shin Chang
submission deadline 20 Oct 2025 | Viewed by 251 | Submission Open
Keywords: biomarkers; cancer genomics; diagnosis; single nucleotide polymorphism (SNP); prognosis
(This special issue belongs to the Section Disease Biomarkers)
State of the Art in Cardiac Imaging
edited by
submission deadline 25 Oct 2025 | 2 articles | Viewed by 3075 | Submission Open
Keywords: cardiology; imaging; scintigraphy; SPECT; PET; computed tomography; magnetic resonance; echocardiography; heart failure; coronary artery disease
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Innovations and Artificial Intelligence in Interventional Radiology: A Step Towards Personalized Medicine
edited by , Giuseppe Pellegrino and Salvatore Alessio Angileri
submission deadline 25 Oct 2025 | 1 articles | Viewed by 871 | Submission Open
Keywords: interventional radiology; artificial intelligence; augmented reality
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Therapeutic Strategies and Future Perspectives for Infectious Diseases
edited by Duduzile Ndwandwe
submission deadline 25 Oct 2025 | Viewed by 143 | Submission Open
Keywords: infectious diseases; antimicrobial resistance; therapeutic strategies; pandemic preparedness; innovative treatments; personalized medicine; artificial intelligence in health; global health equity
(This special issue belongs to the Section Epidemiology)
State of the Art in Pathogenesis and Targeted Therapy in Chronic Obstructive Pulmonary Disease
edited by Emanuela Tudorache
submission deadline 30 Oct 2025 | Viewed by 137 | Submission Open
Keywords: COPD; effective treatments; molecular; genetic; inflammation; biomarkers for diagnosis and prognosis; personalized medicine; novel drug delivery systems; patient outcomes; clinical practice
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Innovations in Airway Diseases
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3325 | Submission Open
Keywords: airway pathophysiology; respiratory therapeutics; novel diagnostic techniques; personalized medicine; clinical trials in airway diseases; innovative treatment strategies; molecular mechanisms; biotechnological advances; environmental impacts; advanced diagnostic tools
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Physical Medicine and Rehabilitation: Pediatrics, Adolescents and the Elderly submission deadline 31 Oct 2025 | 1 articles | Viewed by 3322 | Submission Open
Keywords: personalized medicine; physical medicine; exercise; rehabilitation; pediatrics; adolescents; elderly
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Novel Challenges and Therapeutic Options for Digestive and Liver Diseases—2nd Edition submission deadline 31 Oct 2025 | 1 articles | Viewed by 1703 | Submission Open
Keywords: digestive disease; gastrointestinal disease; pancreas; gallbladder; liver disease; therapy; management; microbiota; drugs; diagnosis
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Neurodevelopmental Disorders: Challenges and Opportunities
edited by Song-Yu Yang, Xue-Ying He and Manfred Philipp
submission deadline 31 Oct 2025 | 1 articles | Viewed by 996 | Submission Open
Keywords: intellectual disability; inborn metabolic disorders; X-linked disorders; retarded growth; mitochondrial diseases; genetic and genomic disorders
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Developments in Cancer Biomarkers for Diagnosis and Prognosis
edited by
submission deadline 31 Oct 2025 | Viewed by 549 | Submission Open
Keywords: cancer biomarkers; diagnosis; prognosis; therapy response biomarkers; miRNA; RNA; DNA; and proteins; cell-free biomarkers; saliva; serum; and plasma; inflammation; metabolites
(This special issue belongs to the Section Disease Biomarkers)
Current Status and Future Prospects of Histopathology in Cancer Diagnosis
edited by Serena Ammendola and
submission deadline 31 Oct 2025 | Viewed by 519 | Submission Open
Keywords: histopathology; cancer diagnostics; cancer biology; prognostic markers; targeted therapy; immunohistochemistry; molecular biology; digital pathology; artificial intelligence
(This special issue belongs to the Section Mechanisms of Diseases)
Clinical Updates and Challenges of Gynecological Cancers
edited by Ottavia D’oria, and Andrea Etrusco
submission deadline 31 Oct 2025 | Viewed by 247 | Submission Open
Keywords: gynecological cancers; ovarian cancer; cervical cancer; endometrial cancer; personalized oncology; biomarkers in gynecology; immunotherapy; surgical oncology; survivorship and quality of life; genetic profiling
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Towards Personalized Medicine in Breast Cancer
edited by Eun Young Kim
submission deadline 31 Oct 2025 | Viewed by 176 | Submission Open
Keywords: personalized medicine; breast cancer; targeted therapy; immunotherapy; pharmacogenomics; biomarkers; treatment resistance; early detection
(This special issue belongs to the Section Mechanisms of Diseases)
Chronic Obstructive Pulmonary Disease (COPD): From Diagnosis and Comorbidities to Personalized Management and Palliative Care
edited by and Florin Mihaltan
submission deadline 10 Nov 2025 | 2 articles | Viewed by 15546 | Submission Open
Keywords: risk factors; systemic inflammation; phenotypes; cardio-pulmonary functional assessment; comorbidities; exacerbations; treatment; rehabilitation; prognosis tools; palliative care; management
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Chemotherapy and Hematopoietic Stem Cell Transplantation
edited by
submission deadline 15 Nov 2025 | Viewed by 140 | Submission Open
Keywords: hematopoietic stem cell transplantation; chemotherapy toxicity and conditioning regimens; graft-versus-host disease (GVHD) management; immunotherapy and cellular therapies
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Ehealth, Telemedicine, and AI in the Precision Medicine Era
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 18752 | Submission Open
Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Neurodegenerative Diseases: Molecular Pathology and Personalized Treatment submission deadline 20 Nov 2025 | 2 articles | Viewed by 7365 | Submission Open
Keywords: neurodegeneration; molecular pathology; precision medicine; biomarkers; personalized therapeutics
(This special issue belongs to the Section Mechanisms of Diseases)
Skin Pathophysiology and Management
edited by , Joanna Goldberg and Mahsa Babaei
submission deadline 20 Nov 2025 | 2 articles | Viewed by 7358 | Submission Open
Keywords: skin disease pathophysiology; skin disease diagnosis; skin disease treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Mechanisms of Airway Inflammation in Asthma
edited by Kathleen Haley
submission deadline 20 Nov 2025 | Viewed by 470 | Submission Open
Keywords: asthma; inflammation in asthma; targeted therapies; acute respiratory distress syndrome; chronic lung diseases; critical care
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology submission deadline 20 Nov 2025 | Viewed by 275 | Submission Open
Keywords: liquid biopsy; lung cancer; biomarkers; diagnosis; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Gynecological Endoscopy: From Personalized Diagnosis to Tailored Surgical Interventions
edited by , Dimitrios Zacharakis and
submission deadline 25 Nov 2025 | 2 articles | Viewed by 4767 | Submission Open
Keywords: gynecological endoscopy; minimally invasive and robotic surgeries; personalized gynecological care; gynecological healthcare; personalized diagnosis; genomic profiling; real-time imaging; AI algorithms; biomarker identification  
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 25 Nov 2025 | 4 articles | Viewed by 3947 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Gynecology and Obstetrics submission deadline 25 Nov 2025 | 1 articles | Viewed by 2157 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Molecular Pathology in Cancer Research
edited by Maurizio Martini and Giuseppe Giuffré
submission deadline 25 Nov 2025 | 1 articles | Viewed by 1183 | Submission Open
Keywords: molecular pathology; diagnostic pathology; cancer diagnosis; biomarkers; targeted therapy; genomics
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical Management and Personalized Treatment in Digestive Surgery submission deadline 25 Nov 2025 | Viewed by 360 | Submission Open
Keywords: digestive disease; digestive cancers; gastrointestinal surgery; stomach; pancreas; liver
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Spine Surgery: Updates and Challenges
edited by Mark James Lambrechts
submission deadline 25 Nov 2025 | Viewed by 162 | Submission Open
Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Head and Neck Disease: Personalized Approaches to Screening and Diagnosis
edited by Heejin Kim
submission deadline 25 Nov 2025 | Viewed by 105 | Submission Open
Keywords: otolaryngology; head and neck; rhinosinusitis; thyroidectomy; tonsillectomy; personalized; screening; diagnosis
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Towards Precision Anesthesia and Pain Management
edited by , Joseph V. Pergolizzi and Filomena Puntillo
submission deadline 30 Nov 2025 | 4 articles | Viewed by 12884 | Submission Open
Keywords: precision medicine; anesthesia; pain medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Computer-Assisted Diagnosis and Personalized Treatment of Fracture
edited by Juan Jiménez-Delgado
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4520 | Submission Open
Keywords: fracture diagnosis; computer-assisted simulation; artificial intelligence in orthopedics; medical imaging advances; personalized fracture treatment; computational fracture analysis; surgical planning tools; virtual reality in orthopedics; forensic analysis of fractures; multiscale modeling of bone
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Insights into Personalized Medicine for Anesthesia and Pain
edited by and Guen Joo Choi
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3811 | Submission Open
Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain
(This special issue belongs to the Section Personalized Medical Care)
Clinical Advances and Innovations in Reconstructive and Plastic Surgery
edited by Laura Răducu
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3508 | Submission Open
Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Role of Genetic Tools in Diagnosis and Personalized Treatment for Neurological Diseases
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2272 | Submission Open
Keywords: neurological disorders; molecular modeling; bioinformatics; genetic tools; genetic variants; omic technologies; DNA sequencing; newborn screening; therapeutic procedure; mechanism of action
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Epigenetics in Precision Medicine: From Mechanism to Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 1684 | Submission Open
Keywords: epigenetics; precision medicine; methylation; histone modifications; non-coding RNA
(This special issue belongs to the Section Epigenetic Therapy)
Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives
edited by Roberta Carbonara and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1675 | Submission Open
Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine
edited by Jerome Rene Lechien
submission deadline 30 Nov 2025 | 3 articles | Viewed by 1416 | Submission Open
Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Gastrointestinal Surgical Oncology
edited by and Myoung-Won Son
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1379 | Submission Open
Keywords: personalized medicine; gastrointestinal surgical oncology; laparoscopic surgery; robotic surgery; AI in surgery; multimodal treatment; clinical trials; oncological outcomes
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers
edited by Gustavo Fabregat-Cid
submission deadline 30 Nov 2025 | Viewed by 201 | Submission Open
Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Obstetrics and Gynaecology
edited by
submission deadline 30 Nov 2025 | Viewed by 171 | Submission Open
Keywords: precision medicine; reproductive health; preeclampsia; gestational diabetes; ovarian cancer; targeted therapies; endometriosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Artificial Intelligence in Personalized Management of Cardiovascular Diseases submission deadline 30 Nov 2025 | Viewed by 170 | Submission Open
Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy; ethics; and governance
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Acute Myeloid Leukemia: Current Progress and Future Directions submission deadline 10 Dec 2025 | 1 articles | Viewed by 1762 | Submission Open
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Complications in Vascular Surgery: Current Updates and Perspectives
edited by
submission deadline 10 Dec 2025 | Viewed by 195 | Submission Open
Keywords: endoleak; visceral ischaemia; lower limb ischaemia; graft infection; aneurysm shrinkage; sac growing; transient ischemic attack; stroke; deep vein thrombosis; vascular injuries; embolization
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Oral Health: Innovative and Personalized Approaches
edited by , Heleni Vastardis and
submission deadline 15 Dec 2025 | 3 articles | Viewed by 2913 | Submission Open
Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
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