Special Issue "Antifungal Immunity and Fungal Vaccine Development"
A special issue of Journal of Fungi (ISSN 2309-608X).
Deadline for manuscript submissions: 30 November 2020.
Interests: invasive fungal infections in immunocompromised children; fungal-host interaction; immunotherapy against invasive fungal infections
Fungi are a vast group of heterotrophic organisms that can grow in a wide repertoire of ecological niches. Even though it is estimated that there are more than 3.6 million species, only 120,000 have been identified and parts of their biology described. Thus far, about 300 fungal species have evolved strategies to be pathogenic to humans, and these are the main focus of medical mycology.
Fungal infections are a significant burden to the human, representing about 15% of hospital-acquired infections, and a recurrent problem to ambulant immunosuppressed patients and people living on the margins of society. Thus far, we have limited knowledge about the underlying mechanisms of the host–fungus interaction and the molecular determinants of pathogenicity for most of the pathogenic species. This has been translated into a limited number of therapeutic drugs to control fungal pathogens. In addition, natural or acquired drug resistance of fungal isolates is now a common problem faced by physicians.
Therefore, greater efforts are still required to find therapeutic alternatives to curve these pathogens. In the last two decades, basic aspects of the fungal immune sensing have been described, and we have now a detailed panorama of the ligand-receptor interactions that lead to the activation of immune effectors for pathogen control. Despite this knowledge, no vaccine against a fungal pathogen is currently available and the immunomodulatory alternatives put in practice are extremely limited. To raise awareness among the community about the importance of this issue and to highlight the current progress in this field, we offer this Special Issue on antifungal immunity and fungal vaccine development.
Prof. Dr. Hector M. Mora-Montes
Prof. Dr. Thomas Lehrnbecher
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- host-fungus interaction