Yeast Genetics 2022

Dear Colleagues,

The yeast Saccharomyces cerevisiae, along with being a crucial industrial microorganism, also represents a model organism for the investigation of the majority of biological processes in eukaryotes. This conventional yeast was the first eukariote to be successfully transformed with exogenous DNA. Due to efficient homologous recombination between transforming DNA and its genome, it is easy to precisely genetically modify this yeast, allowing the construction of both biotechnologically relevant strains and strains for application in scientific research. On the other hand, there is a huge number of uncharacterized or poorly characterized nonconventional yeasts, many of which are known to have certain advantages over conventional yeasts, such as efficient use of alternative carbon sources, higher resistance to growth and fermentation inhibitors, production of interesting metabolites, etc. However, for a great majority of these nonconventional yeasts, the construction of desired strains is not yet a routine procedure because the molecular tools needed for precise modification of their genome have not been developed yet. Therefore, this Special Issue focuses on research on the genetics of conventional and nonconventional yeast, as well as development of molecular tools for targeted modification of yeasts and genomes and construction of potentially biotechnologically relevant yeast strains.

Dr. Ivan-Krešimir Svetec
Dr. Marina Svetec Miklenić
Guest Editor

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