Journal of Clinical Medicine

Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Knee Arthroplasty: Recent Advances and Future Challenges

edited by Matteo Marullo

submission deadline 25 Aug 2026 | Viewed by 29 | Submission Open

Keywords: knee arthroplasty; implant design; robotic surgery; revision surgery; biomechanics; clinical outcomes; perioperative care; fast-track surgery; digital orthopedics; partial knee replacement

(This special issue belongs to the Section Orthopedics)

Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management—Second Edition

edited by Emelina Stambolliu and Antonios A. Argyris

submission deadline 25 Aug 2026 | Viewed by 7 | Submission Open

Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds

(This special issue belongs to the Section Vascular Medicine)

Motor Activity and Cognitive Development in Early Childhood: Clinical Implications

edited by

Michele Roccella

and

Daniela Smirni

submission deadline 25 Aug 2026 | Viewed by 6 | Submission Open

Keywords: motor activity; cognitive development; early childhood; neurodevelopmental disorders; autism spectrum disorder; attention-deficit/hyperactivity disorder; developmental coordination disorder; preterm birth

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates in Heart Failure: Innovations in Diagnosis, Therapy and Management

edited by Paolo Severino

submission deadline 28 Aug 2026 | Viewed by 23 | Submission Open

Keywords: heart failure; HFrEF therapy; HFpEF phenotyping; right ventricular dysfunction; renal congestion assessment; diuretic resistance; NT-proBNP dynamics; cardiac imaging; post-discharge management

(This special issue belongs to the Section Cardiology)

Clinical Management of Type 1 Diabetes: 2nd Edition

edited by Carmen Quirós

submission deadline 31 Aug 2026 | Viewed by 7 | Submission Open

Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens

(This special issue belongs to the Section Endocrinology & Metabolism)

Optimizing the Surgical Journey: From Abdominal Operation to Recovery

edited by

Alessio Giordano

and Carlo Bergamini

submission deadline 1 Sep 2026 | Viewed by 28 | Submission Open

Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist

(This special issue belongs to the Section General Surgery)

Current Challenges in Clinical Dentistry: 3rd Edition

edited by

Eiji Tanaka

and

Susumu Abe

submission deadline 15 Sep 2026 | Viewed by 42 | Submission Open

Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Treatment and Clinical Management of Necrotizing Pancreatitis

edited by

Apostolos Gaitanidis

submission deadline 20 Sep 2026 | Viewed by 46 | Submission Open

Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Management in Dry Eye Disease: Current Strategies and Emerging Protocols

edited by Sunil Shah and Raquel Gil-Cazorla

submission deadline 20 Sep 2026 | Viewed by 31 | Submission Open

Keywords: dry eye disease; ocular surface; diagnostics; inflammation; biomarkers; emerging therapies

(This special issue belongs to the Section Ophthalmology)

Advances in the Diagnosis and Management of Sarcoidosis

edited by

Carlos Feijoo-Massó

, Pilar Brito-Zerón and Miriam Akasbi Montalvo

submission deadline 25 Sep 2026 | Viewed by 27 | Submission Open

Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease

(This special issue belongs to the Section Immunology & Rheumatology)

Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO

edited by Tsachi Tsadok Perets

submission deadline 30 Sep 2026 | Viewed by 5 | Submission Open

Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Hepatology

edited by

Dimitrios S. Karagiannakis

and

Theodoros Androutsakos

submission deadline 30 Sep 2026 | Viewed by 3 | Submission Open

Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Fibromyalgia: Diagnostic Progress and Therapeutic Advances

edited by

Casandra Isabel Montoro Aguilar

submission deadline 17 Nov 2026 | Viewed by 55 | Submission Open

Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS

(This special issue belongs to the Section Clinical Neurology)

Dental Care: Oral and Systemic Disease Prevention: 2nd Edition

edited by

Kacper Nijakowski

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1520 | Submission Open

Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications

edited by

Petroula N. Nana

, Tilo Kölbel and José Ignacio F. Torrealba

submission deadline 20 Jul 2027 | Viewed by 131 | Submission Open

Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes

(This special issue belongs to the Section Vascular Medicine)

Insights into Urological Surgery: Evolving Practices, Trends, and Emerging Challenges

edited by