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Special Issue "The Role of Endocrine Disrupting Chemicals in the Feto-Placental Unit and Female Reproduction"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 31 December 2019

Special Issue Editors

Guest Editor
Dr. Emmanouil Karteris

Department of Life Science, Brunel University London, Uxbridge UB8 3PH, UK
Website | E-Mail
Interests: role of endocrine disrupting chemicals in the feto-placental unit; use of next generation of rapalogues as therapeutic agents against ovarian cancer; detection and characterisation of circulating tumour cells; use of liquid biopsies as cancer biomarkers of diagnostic and prognostic value; development of fetal-placental 3D cultures as a screening platform for EDCs
Guest Editor
Dr. Ioannis Kyrou

Aston Medical School, Aston University, Birmingham B4 7ET, UK
Website | E-Mail
Interests: metabolism and energy homeostasis; nutrition; exercise and health; epidemiology of non-communicable diseases and public health; obesity and obesity-related complications; type 2 diabetes; cardiovascular diseases; endocrinology; endocrine disrupting chemicals; Polycystic Ovary Syndrome (PCOS); Non-Alcoholic Fatty Liver Disease (NAFLD); mental health-stress and the HPA axis
Guest Editor
Prof. Dr. Harpal S. Randeva

Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK
Website | E-Mail
Interests: reproductive endocrinology; Polycystic Ovary Syndrome (PCOS); endocrine disrupting chemicals; metabolism and energy homeostasis; obesity; diabetes; adrenal and cardiovascular endocrinology; cardiovascular disease; non-alcoholic fatty liver disease; molecular biology of orexins and their receptors; nutrition; exercise

Special Issue Information

Dear Colleagues,

Endocrine disrupting chemicals (EDCs) are environmental chemicals that interfere with physiological systems, adversely affecting the hormonal balance within various endocrine axes (particularly within the female reproductive system) or disrupting normal function in the target organs that these hormones regulate. EDCs include a variety of chemicals classes, such as industrial by-products, pesticides, and chemicals, used in manufacturing (particularly plastics). The US Centers for Disease Control and Prevention (CDC) have reported that more than 90% of 2000 individuals tested positive for chemicals in their blood. Moreover, in a report to the WHO (The State of the Science of Endocrine Disrupting Chemicals-2012), key concerns were raised regarding the “high incidence and the increasing trends of many endocrine-related disorders in humans”.

Emerging studies have linked EDCs with disorders at the placental level, -impact  later in adult life. Contributions to this Special Issue will advance our understanding of the role of EDCs in placentation, placental development and placental functions, which are key events for successful reproductive outcomes, as well as female reproduction as a whole. Moreover, we will be addressing how in utero exposures can adversely affect adult life.

Dr. Emmanouil Karteris
Dr. Ioannis Kyrou
Prof. Dr. Harpal S. Randeva
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • EDCs
  • placenta
  • fetus
  • female reproduction
  • exposures
  • pregnancy
  • toxicity

Published Papers

This special issue is now open for submission.
J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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