New Advances in Clinical Genetics and Genetic Epidemiology

Dear Colleagues,

Genetic predispositions and risks are major factors for disease occurrence as well as progression. In recent decades, different approaches have been introduced and provided us with opportunities for large-scale, high-throughput genetic studies in population, including array methods, sequencing, etc. The understanding of the mechanisms for diseases have therefore changed rapidly. For example, genetic variants or mutations may also serve as an important factor for cancers other than familial cancer syndromes; cumulative common variants may contribute significantly to disease occurrence; variants in specific non-coding regions may affect the epigenetic regulation of gene expressions; etc. More importantly, biomarkers and prediction tools have been developed via clinical translational studies based on these findings which provide additional tools for disease evaluation. In this Special Issue, we invite authors to submit their works on clinical genetics and genetic epidemiology studies for different diseases. This may involve: (1) the investigations of germline or somatic variants; (2) germline or somatic variants in specific non-coding regions which may affect the epigenetic regulation of gene expressions; (3) translational research based on germline or somatic variants; (4) populational genetic association studies, family history study for underrepresented populations in the research field, etc.

Dr. Rong Na
Dr. Wenquan Niu
Dr. Haitao Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.