Obstructive Sleep Apnea Syndrome: Pathogenesis, Treatments and Comorbidity

Dear Colleagues,

Obstructive Sleep Apnea (OSA) is a common health problem characterized by repeated apneic events during sleep, resulting from a mechanical obstruction due to a decreased muscle tone of the upper airway. The OSA syndrome includes, among others symptoms, the occurrence of excessive daytime sleepiness due to poor quality sleep. Although continuous positive airway pressure is considered the treatment of choice, suboptimal acceptance and progressively reduced adherence rates can limit its efficacy. Therefore, several studies focused on the identification of the causes that could justify the nonadherence of some subjects to the prescribed therapeutic approach, evaluating their psychosocial behavior and personality traits.

As a whole, OSA can be considered a multifactorial disease; indeed, a multidisciplinary approach might be the best option to deepen the pathogenetic aspects of a syndrome that sees juxtaposed researchers from different medical specialties: internists, pulmonologists, cardiologists, ophthalmologists, otolaryngologists, clinical pharmacologists, psychologists, and nutritionists.

This Special Issue has the ambitious goal of highlighting how multidisciplinary approaches can contribute to the improvement of knowledge on the pathogenetic mechanisms of OSA and related comorbidities, therefore, with the aim of improving the quality of life of the subjects affected by OSA and also to suggest preventive interventions and care.

Prof. Dr. Francesca Romana Patacchioli
Guest Editor

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