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We are delighted to share our collection of notable review papers published in the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) in the past two years. These 12 papers were selected based on their high number of average views, downloads, and citations, reflecting their broad influence in the field. These review papers cover a wide range of topics in the clinical field and highlight trending research topics. We hope they offer some useful insights and allow you to further develop your research background.

1. “Non-Surgical Approaches to the Management of Lumbar Disc Herniation Associated with Radiculopathy: A Narrative Review”
by Ahmed M. El Melhat, Ahmed S. A. Youssef, Moustafa R. Zebdawi, Maya A. Hafez, Lamia H. Khalil and Deed E. Harrison
J. Clin. Med. 2024, 13(4), 974; https://doi.org/10.3390/jcm13040974
Full text available online: https://www.mdpi.com/2077-0383/13/4/974

2. “Treatment of Acute Kidney Injury: A Review of Current Approaches and Emerging Innovations”
by Christina Tamargo, Mohamad Hanouneh and C. Elena Cervantes
J. Clin. Med. 2024, 13(9), 2455; https://doi.org/10.3390/jcm13092455
Full text available online: https://www.mdpi.com/2077-0383/13/9/2455

3. “Portal Vein Thrombosis: State-of-the-Art Review”
by Andrea Boccatonda, Simone Gentilini, Elisa Zanata, Chiara Simion, Carla Serra, Paolo Simioni, Fabio Piscaglia, Elena Campello and Walter Ageno
J. Clin. Med. 2024, 13(5), 1517; https://doi.org/10.3390/jcm13051517
Full text available online: https://www.mdpi.com/2077-0383/13/5/1517

4. “Critical Care Management of Severe Asthma Exacerbations”
by Shameek Gayen, Stephen Dachert, Bilal H. Lashari, Matthew Gordon, Parag Desai, Gerard J. Criner, Juan Carlos Cardet and Kartik Shenoy
J. Clin. Med. 2024, 13(3), 859; https://doi.org/10.3390/jcm13030859
Full text available online: https://www.mdpi.com/2077-0383/13/3/859

5. “Clinical Recommendations for Managing Genitourinary Adverse Effects in Patients Treated with SGLT-2 Inhibitors: A Multidisciplinary Expert Consensus”
by Juan J. Gorgojo-Martínez, José L. Górriz, Ana Cebrián-Cuenca, Almudena Castro Conde and María Velasco Arribas
J. Clin. Med. 2024, 13(21), 6509; https://doi.org/10.3390/jcm13216509
Full text available online: https://www.mdpi.com/2077-0383/13/21/6509

6. “Antiphospholipid Syndrome: A Comprehensive Clinical Review”
by Vasileios Patriarcheas, Georgios Tsamos, Dimitra Vasdeki, Elias Kotteas, Anastasios Kollias, Dimitris Nikas, Georgia Kaiafa and Evangelos Dimakakos
J. Clin. Med. 2025, 14(3), 733; https://doi.org/10.3390/jcm14030733
Full text available online: https://www.mdpi.com/2077-0383/14/3/733

7. “Septic Cardiomyopathy: Difficult Definition, Challenging Diagnosis, Unclear Treatment”
by George E. Zakynthinos, Grigorios Giamouzis, Andrew Xanthopoulos, Evangelos Oikonomou, Konstantinos Kalogeras, Nikitas Karavidas, Ilias E. Dimeas, Ioannis Gialamas, Maria Ioanna Gounaridi, Gerasimos Siasos et al.
J. Clin. Med. 2025, 14(3), 986; https://doi.org/10.3390/jcm14030986
Full text available online: https://www.mdpi.com/2077-0383/14/3/986

8. “Cardiovascular–Kidney–Metabolic Syndrome: A New Paradigm in Clinical Medicine or Going Back to Basics?”
by Victoria Mutruc, Cristina Bologa, Victorița Șorodoc, Alexandr Ceasovschih, Bianca Codrina Morărașu, Laurențiu Șorodoc, Oana Elena Catar and Cătălina Lionte
J. Clin. Med. 2025, 14(8), 2833; https://doi.org/10.3390/jcm14082833
Full text available online: https://www.mdpi.com/2077-0383/14/8/2833
 
9. “Acute Respiratory Distress Syndrome: Pathophysiological Insights, Subphenotypes, and Clinical Implications—A Comprehensive Review”
by Mairi Ziaka and Aristomenis Exadaktylos
J. Clin. Med. 2025, 14(15), 5184; https://doi.org/10.3390/jcm14155184
Full text available online: https://www.mdpi.com/2077-0383/14/15/5184

10. “Now and the Future: Medications Changing the Landscape of Cardiovascular Disease and Heart Failure Management”
by Thomas Oswald, Steven Coombs, Susan Ellery and Alexander Liu
J. Clin. Med. 2025, 14(11), 3948; https://doi.org/10.3390/jcm14113948
Full text available online: https://www.mdpi.com/2077-0383/14/11/3948

11. “IgA Vasculitis (Henoch–Schönlein Purpura): An Update on Treatment”
by Santos Castañeda, Patricia Quiroga-Colina, Paz Floranes, Miren Uriarte-Ecenarro, Cristina Valero-Martínez, Esther F. Vicente-Rabaneda and Miguel A. González-Gay
J. Clin. Med. 2024, 13(21), 6621; https://doi.org/10.3390/jcm13216621
Full text available online: https://www.mdpi.com/2077-0383/13/21/6621

12. “A Comprehensive Review of Catheter-Related Thrombosis”
by Marina López-Rubio, Marta-Olimpia Lago-Rodríguez, Lucía Ordieres-Ortega, Crhistian-Mario Oblitas, Sergio Moragón-Ledesma, Rubén Alonso-Beato, Luis-Antonio Alvarez-Sala-Walther and Francisco Galeano-Valle
J. Clin. Med. 2024, 13(24), 7818; https://doi.org/10.3390/jcm13247818
Full text available online: https://www.mdpi.com/2077-0383/13/24/7818