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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondria: Central Players in Cancer submission deadline 20 Mar 2026 | 3 articles | Viewed by 2877 | Submission Open
Keywords: mitochondria; cancer; tumorigenesis; oxidative phosphorylation; glycolysis; Warburg effect; reactive oxygen species (ROS); apoptosis; mitochondrial dysfunction; metabolic reprogram-ming; cancer therapy
(This special issue belongs to the Section Molecular Biology)
New Trends and Challenges in Chronic Diseases
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 2812 | Submission Open
Keywords: chronic diseases; ER stress; oxidative stress; immune regulation; new pathways of pathogenesis; cancer development
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring Phage–Host Interactions: Novel Findings and Perspectives
edited by
submission deadline 20 Mar 2026 | 3 articles | Viewed by 2199 | Submission Open
Keywords: bacteriophages; phage therapy; phage/bacteria interactions; genomics; transcriptomics; proteomics; metabolomics; biofilms
(This special issue belongs to the Section Molecular Microbiology)
How Aging Results in Cognitive Decline: Molecular Mechanisms
edited by Holly Christian Hunsberger
submission deadline 20 Mar 2026 | 1 articles | Viewed by 2189 | Submission Open
Keywords: aging; memory; hippocampus; neurodegeneration; sex; gender; exercise; synapses; metabolism; mitochondria
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research on Kidney Disease/Renal Dysfunction
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 2186 | Submission Open
Keywords: kidney disease/renal dysfunction; hypoxia-inducible factor-prolyl hydroxylase (HIF-PHD) inhibitors; renal anemia; chronic renal faikure
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Breeding for Abiotic Stress Tolerance in Crops (Second Edition)
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 2144 | Submission Open
Keywords: plant breeding; advance molecular approach; molecular characterization; environmental stresses plant tolerance; resistant genes; QTLs; drought; salinity; climatic changes
(This special issue belongs to the Section Molecular Plant Sciences)
Steatotic Liver Disease: From Bench to Bedside and Back
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1932 | Submission Open
Keywords: MASLD; ALD; MetALD; fibrosis; hepatocellular carcinoma; molecular mechanisms; molecular markers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism and Therapeutic Approach of Metal Toxicity
edited by Grażyna Gromadzka
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1830 | Submission Open
Keywords: metal toxicity; neurodegenerative disease; cancer; stroke; myocardial infarct; atherosclerosis; cardiovascular disease; metal chelators; therapeutic approach of metal toxicity; cobalt toxicity; copper toxicity; iron toxicity; aluminum toxicity; manganese toxicity; molybdenum toxicity; nickel toxicity; zinc toxicity; lead toxicity
(This special issue belongs to the Section Molecular Toxicology)
Parkinson’s Disease and Related Diseases: Mechanisms, Genetic Factors and Treatments
edited by
submission deadline 20 Mar 2026 | 3 articles | Viewed by 1818 | Submission Open
Keywords: Parkinson’ s disease; neurodegenerative disorders; α -synuclein aggregation; neuroinflammation; gene therapy; biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
The Role and Mechanisms of Natural Products in Inflammatory Responses and Inflammatory Diseases
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1654 | Submission Open
Keywords: natural product; bioactive component; inflammation; inflammatory disease; anti-inflammatory; mechanism
(This special issue belongs to the Section Molecular Immunology)
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