Steatotic Liver Disease: From Bench to Bedside and Back
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 240
Special Issue Editor
Interests: metabolic syndrome; insulin resistance; chronic hepatitis C; liver; antioxidants; mesenchymal stem cell; inflammatory biomarkers; liver diseases; fatty liver; diabetes; hepatitis; cirrhosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Steatotic Liver Disease (SLD), including Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD), Alcohol-associated Liver Disease (ALD) and the mixed form MetALD, represents a major health concern wordwide. In the last years, the burden of liver-related morbidity and mortality is rapidly growing especially because of the global epidemic of SLD. Translational research aims to identify molecular mechanisms relevant to the pathogenesis of diseases in order to discover novel therapeutic targets. This special issue will accept translational studies shedding light on the molecular bases of MASLD, ALD and MetALD with particular interest on the crosstalk between the liver and other organs (particularly the gut, the adipose tissue and the muscle). Translational studies in in vitro and in vivo models of SLD, focusing on glucose metabolism and insulin signaling, lipoprotein metabolism and lipotoxicity, oxidative stress and inflammation, fibrosis and oncogenesis, are welcome. Clinical studies identifying molecular markers for the prediction of liver outcomes are also welcome.
Dr. Federico Salomone
Guest Editor
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Keywords
- MASLD
- ALD
- MetALD
- fibrosis
- hepatocellular carcinoma
- molecular mechanisms
- molecular markers
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