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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Nutrient Uptake and Utilization in Plants

edited by

Stella Karydogianni

submission deadline 30 Nov 2026 | Viewed by 503 | Submission Open

Keywords: agriculture and crop improvement; molecular and cellular mechanisms; nitrogen; nutrient efficiency; protein

(This special issue belongs to the Section Molecular Plant Sciences)

Bridging the Omics of Protein Landscape of Aging and Disease: New Insights and Opportunities

edited by

Fátima Milhano Santos

submission deadline 30 Nov 2026 | Viewed by 500 | Submission Open

Keywords: age-related disease; aging; biomarkers; chronic diseases; neurodegenerative diseases; ocular diseases; proteomics; kidney diseases

(This special issue belongs to the Section Molecular Biology)

Nutrition of Crustaceans: A Molecular Perspective

edited by

Cheng Chi

submission deadline 30 Nov 2026 | Viewed by 496 | Submission Open

Keywords: crustacean nutrition; molecular mechanisms; aquaculture; nutrient metabolism; reproduction

(This special issue belongs to the Section Molecular Biology)

Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification

edited by

Ágnes Szepesi

submission deadline 30 Nov 2026 | Viewed by 494 | Submission Open

Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano–bio interactions; crop production; plant-based solutions; bio-corona

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Probiotics and Prebiotics in Gut Health and Disease

edited by

Hikmate Abriouel

submission deadline 30 Nov 2026 | Viewed by 488 | Submission Open

Keywords: probiotics; prebiotics; gut microbiota; intestinal health; dysbiosis; host–microbe interactions; omics; gut–brain axis

(This special issue belongs to the Section Molecular Microbiology)

Bioactive Peptides from Natural Sources: Pharmacological Effects, Recombinant Expression, Modification, Molecular Mechanisms, and Therapeutic Potential

edited by Linchun Shi

submission deadline 30 Nov 2026 | Viewed by 484 | Submission Open

Keywords: bioactive peptides; functional peptides; antimicrobial peptides; host-defense peptides; venom peptides; ribosomally synthesized and post-translationally modified peptides; peptide precursor gene families; comparative genomics; phylogeny; structure–activity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Peptides in Healthcare and Beyond: Emerging Roles in Skincare, Nutrition, Medicine, and Animal Health

edited by

Jiazhong Li

and Lijing Fang

submission deadline 30 Nov 2026 | Viewed by 484 | Submission Open

Keywords: peptides; efficacy; healthcare; skincare; nutrition; medicine; animal health

(This special issue belongs to the Section Biochemistry)

Mitochondrial DNA and Its Multiple Functions in Health and Disease

edited by

Izinara Rosse

and Vanessa F. Gonçalves

submission deadline 30 Nov 2026 | Viewed by 483 | Submission Open

Keywords: mitochondrial DNA; mtDNA; mitochondrial genome sequencing; mitochondrial dysfunction; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Influence of Genetics on Lymphatic System Diseases

edited by

Tomomi Watanabe-Asaka

submission deadline 30 Nov 2026 | Viewed by 473 | Submission Open

Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular and Cellular Pathways Involved in Age-Related Musculoskeletal Disorders

edited by

Abhishek Chandra

and Neha Dole

submission deadline 30 Nov 2026 | Viewed by 469 | Submission Open

Keywords: musculoskeletal disorders; cellular senescence; aging; genetic mutations; oxidative stress; mitochondrial dysfunction; bone homeostasis

(This special issue belongs to the Section Molecular Biology)

Molecular, Cellular and Systems Research on Neuroanatomy, Brain Function and Its Impact on Human Behavior

edited by

Frank Schmitz

submission deadline 30 Nov 2026 | Viewed by 466 | Submission Open

Keywords: central nervous system; neuroanatomy; human behavior; nuclei; neuronal circuits; connectivity channels

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Central Nervous System Inflammatory Demyelinating Diseases

edited by Yong Guo

submission deadline 30 Nov 2026 | Viewed by 465 | Submission Open

Keywords: central nervous system; autoimmune; demyelination; inflammation; multiple sclerosis; pathology

(This special issue belongs to the Section Molecular Neurobiology)

Effects of the Environmental Conditions on Bacterial Growth and Functions

edited by

Fernanda Abreu

submission deadline 30 Nov 2026 | Viewed by 462 | Submission Open

Keywords: bacterial growth; growth conditions; gene expression; bioproducts; biofilm; resistance; population dynamics

(This special issue belongs to the Section Molecular Microbiology)

T Cell Malignancies: Translating Basic Research into Better Therapy

edited by

Grzegorz Przybylski

submission deadline 30 Nov 2026 | Viewed by 460 | Submission Open

Keywords: T-Cell malignancies; specific target antigens; gene-targeted therapies

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Periodontitis

edited by Maja Miletić and

Natasa Nikolic-Jakoba

submission deadline 30 Nov 2026 | 1 articles | Viewed by 460 | Submission Open

Keywords: periodontitis; molecular mechanisms; inflammation; oral microbiome; multi-omics; biomarkers; cytokines; oxidative stress; immune regulation; tissue regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Engineering of Antimicrobial Agents: From Structure-Function Insights to Combinatorial Therapies

edited by Mingrui Liao

submission deadline 30 Nov 2026 | Viewed by 459 | Submission Open

Keywords: antimicrobial amphiphiles; antimicrobial resistance; structure–activity relationship; synergistic antimicrobial therapy; drug delivery systems

(This special issue belongs to the Section Molecular Biology)

Understanding and Combating Antimicrobial Resistance: Molecular Insights and Innovative Approaches

edited by

Giovanni Di Bonaventura

submission deadline 30 Nov 2026 | Viewed by 445 | Submission Open

Keywords: genetic mutations; horizontal gene transfer; efflux pump mechanisms; biofilm formation; novel antibiotic development; antimicrobial peptides; phage therapy; CRISPR-based tools; antimicrobial stewardship programs

(This special issue belongs to the Section Molecular Biology)

Research of Aldo-Keto Reductases in Human Disease

edited by

Ping Zhu

and

Hao Luo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 440 | Submission Open

Keywords: aldo-keto reductase (AKR); protein engineering; AKR1B10; cancer biomarker; chemoresistance

(This special issue belongs to the Section Biochemistry)

Molecular Progress in Male Reproduction

edited by

Ahmet Ayaz

submission deadline 30 Nov 2026 | Viewed by 438 | Submission Open

Keywords: male infertility; spermatogenesis; epigenetics; sperm function; testicular molecular biology; bioinformatics; reproductive genomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Advances of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 30 Nov 2026 | Viewed by 435 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

Research on Stress Signaling in Embryonic Development

edited by

Poongodi Geetha-Loganathan

and Norihisa Higashihori

submission deadline 30 Nov 2026 | Viewed by 429 | Submission Open

Keywords: stress signaling; embryonic development; morphogenesis; signal transduction; teratogenesis

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Leukemia

edited by

Juan Manuel Mejia-Arangure

submission deadline 30 Nov 2026 | Viewed by 427 | Submission Open

Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Transcription Factors in Cancer

edited by

Tomasz Wilanowski

submission deadline 30 Nov 2026 | Viewed by 425 | Submission Open

Keywords: transcription factor; oncogene; tumor suppressor; nuclear receptor; genetic regulation; post-translational regulation; biomarker; drug target

(This special issue belongs to the Section Molecular Oncology)

Plant–Microbe Interactions Driving Abiotic Stress Adaptation

edited by Saeed Ur Rahman and Nan Hui

submission deadline 30 Nov 2026 | Viewed by 424 | Submission Open

Keywords: plant–microbe interactions; abiotic stress; rhizosphere microbiome; stress tolerance; horticultural crops; molecular mechanisms; plant growth-promoting microbes; omics approaches; sustainable agriculture; signaling pathways

(This special issue belongs to the Section Molecular Plant Sciences)

Antimicrobial Agents and the Quest for Resistance Breakthroughs

edited by

Inês Bártolo

submission deadline 30 Nov 2026 | Viewed by 420 | Submission Open

Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Research on Neurotransmitters (Second Edition)

edited by

Mario Manto

Hiroshi Mitoma

and Jing-Ning Zhu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 418 | Submission Open

Keywords: neurotransmitters; GABA; glutamate; monoamines; dopamine; serotonin; norepinephrine; neuropeptides; nitric oxide; neurosteroids; stress; neurotrophins; epigenetics; gut–brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Application of Biomaterial in Skin Diseases

edited by

Danuta Nowicka

submission deadline 30 Nov 2026 | Viewed by 417 | Submission Open

Keywords: chronic dermatoses; autologus material; PRP; stem cells; growth factors

(This special issue belongs to the Section Materials Science)

Vascular Calcification: Molecular Regulation, Inflammation and Translational Perspectives

edited by

Laia Cañes

submission deadline 30 Nov 2026 | Viewed by 417 | Submission Open

Keywords: vascular calcification; inflammation; calcium-phosphate alterations; osteogenic differentiation; vascular smooth muscle cells; cardiovascular disease

(This special issue belongs to the Section Molecular Biology)

Recent Genetic Insights into Neurodevelopmental Disorders

edited by Maria Cristina Aspromonte and Emanuela Dazzo

submission deadline 30 Nov 2026 | Viewed by 412 | Submission Open

Keywords: neurodevelopmental disorders; autism spectrum disorder; intellectual disability; attention deficit hyperactivity disorder; epilepsy; motor disorders; chromosomal rearrangements; genetic variant; integrative omics approaches

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Dopamine Neurotransmission in Schizophrenia

edited by

Mirian Akemi Furuie Hayashi

submission deadline 30 Nov 2026 | Viewed by 410 | Submission Open

Keywords: schizophrenia; dopamine; dopaminergic system; neurotransmission; psychosis; pathophysiology; molecular psychiatry

(This special issue belongs to the Section Molecular Neurobiology)

Advances in the Molecular Biology of Lipids and Mitochondria

edited by

Alejandra Espinosa

submission deadline 30 Nov 2026 | Viewed by 405 | Submission Open

Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Integrative Regenerative Medicine: Bridging Molecular Mechanisms and Therapeutic Applications

edited by

Jerran Santos

submission deadline 30 Nov 2026 | Viewed by 400 | Submission Open

Keywords: regenerative medicine; stem cells; molecular mechanisms; tissue engineering; organoids; biomaterials; biofabrication; clinical translation; cell therapy; integrative biology

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms in Mucosal Immunity

edited by

Mónica Vermeulen

submission deadline 30 Nov 2026 | Viewed by 398 | Submission Open

Keywords: mucosal immunity; metabolism; innate memory; trainers and inflammatory stimuli

(This special issue belongs to the Section Molecular Immunology)

Advances in Osteogenesis: 2nd Edition

edited by

Andrea Del Fattore

submission deadline 30 Nov 2026 | Viewed by 395 | Submission Open

Keywords: osteogenesis; osteoblast; bone formation; disease; bone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications

edited by

Ahmet Kertmen

submission deadline 30 Nov 2026 | Viewed by 387 | Submission Open

Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging

(This special issue belongs to the Section Molecular Nanoscience)

Oxidative Stress, Biomarkers and Dysregulated Lipid Metabolism in Cardiovascular Diseases

edited by

Amilia Aminuddin

and Adila Abdul A. Hamid

submission deadline 30 Nov 2026 | 1 articles | Viewed by 385 | Submission Open

Keywords: cardiovascular diseases; oxidative stress; lipid metabolism; atherosclerosis; endothelial dysfunction; inflammation; biomarkers; reactive oxygen species (ROS); dyslipidemia; vascular function

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Apoptosis in Health and Disease: Recent Advances and Future Directions

edited by Shabnam Malik

submission deadline 30 Nov 2026 | Viewed by 385 | Submission Open

Keywords: apoptosis; programmed cell death; health and disease; cellular homeostasis; cancer; neurodegenerative disorders

(This special issue belongs to the Section Molecular Biology)

Therapeutic Strategies for Surgical Tissue Damage, Repair and Regeneration

edited by

Alex K. Wong

submission deadline 30 Nov 2026 | Viewed by 381 | Submission Open

Keywords: surgical injury; tissue regeneration; vasculogenesis; wound healing in compromised settings; molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antiviral Drug Target Discovery and Design

edited by

Dongwei Kang

and Huajun Zhao

submission deadline 30 Nov 2026 | Viewed by 376 | Submission Open

Keywords: antiviral; drug discovery; drug resistance; immune and pharmacological mechanisms; immunotherapy; immunopathology; vaccines and adjuvants

(This special issue belongs to the Section Molecular Pharmacology)

Plant–Microbe Interactions in Alleviation of Abiotic Stress in Plants

edited by

Marzena Sujkowska-Rybkowska

submission deadline 30 Nov 2026 | Viewed by 376 | Submission Open

Keywords: abiotic stresses; plant–microbe interactions; symbiotic microbes; stress adaptation; stress-responsive genes; physio-logical responses

(This special issue belongs to the Section Molecular Plant Sciences)

Roles and Mechanisms of Non-Coding RNAs in Human Health and Disease: 2nd Edition

edited by

Marco Ragusa

and

Cristina Barbagallo

submission deadline 30 Nov 2026 | Viewed by 371 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; polymorphisms; cancer; degenerative diseases; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Insight into Pathogen Stress Effects on Plant Structure and Metabolism

edited by

Edmund Kozieł

and

Katarzyna Otulak-Kozieł

submission deadline 30 Nov 2026 | Viewed by 370 | Submission Open

Keywords: plant–pathogen interaction; innate immunity; ultrastructure; plant defense systems; plant physiology; signal transduction; resistance genes

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insight into Polymer Dynamics

edited by

Sirui Ge

submission deadline 30 Nov 2026 | Viewed by 367 | Submission Open

Keywords: polymer dynamics; glass transition; segmental relaxation; bulk relaxation; structure–property relationship; functional polymers; spectroscopy; instrumental characterization; simulations and modeling; polymer diffusion

(This special issue belongs to the Section Materials Science)

RNA Structure, Folding and Cellular Function: Mechanisms and Biological Significance

edited by

Ilias Skeparnias

submission deadline 30 Nov 2026 | Viewed by 354 | Submission Open

Keywords: RNA structure; RNA folding; RNA–protein interactions; R-loops; RNA:DNA hybrids; non-coding RNA; RNA biogenesis; gene regulation; ribozymes; RNA therapeutics

(This special issue belongs to the Section Molecular Biology)

Natural Product Research: From Isolation to Functional Validation

edited by

Radosław Kowalski

submission deadline 30 Nov 2026 | Viewed by 349 | Submission Open

Keywords: natural products; secondary metabolites; bioactive compounds; extraction and isolation; green extraction; structural elucidation; metabolomics profiling (LC–HRMS/MS); dereplication; functional validation; molecular mechanisms; molecular docking; molecular modeling; ligand–protein interactions; structure–activity relationship (SAR); in vitro and in vivo studies; bioavailability and safety; antimicrobial activity; antioxidant activity; anticancer activity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in the Reprogramming of Mitochondrial Signalling and Metabolism in Cancers

edited by

Maria Rosa Ciriolo

and

Fabio Ciccarone

submission deadline 30 Nov 2026 | Viewed by 349 | Submission Open

Keywords: mitochondrial dynamic; mitochondrial biogenesis; mitochondrial transfer; mitochondrial targeting; mitophagy; oxidative metabolism; mtDNA; ROS; oncometabolism

(This special issue belongs to the Section Molecular Oncology)

Stem Cell Research in Urological, Hepatological, and Ophthalmological Disorders

edited by Yuanyuan Zhang

submission deadline 30 Nov 2026 | Viewed by 347 | Submission Open

Keywords: stem cells; induced pluripotent stem cells (iPSCs); exosomes; tissue regeneration; urinary incontinence; kidney dysfunction; ocular disorders; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Brucella Research

edited by

Angel Oñate

submission deadline 30 Nov 2026 | Viewed by 344 | Submission Open

Keywords: Brucella abortus; molecular pathogenesis; host–pathogen interaction; virulence factors; oxidative stress response; intracellular survival; immune evasion; exosomes; vaccine development

(This special issue belongs to the Section Molecular Microbiology)

The Role of Ferroptosis in Cancer Biology and Therapy

edited by Alessandra Di Paola and Elvira Pota

submission deadline 30 Nov 2026 | Viewed by 334 | Submission Open

Keywords: ferroptosis; cancer biology; tumor microenvironment; therapeutic targeting; anticancer immunity; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Gene Therapy for Ocular Diseases: Mechanisms, Advances and Therapeutic Applications

edited by Jiang-Hui Wang

submission deadline 30 Nov 2026 | Viewed by 326 | Submission Open

Keywords: AAV; capsid engineering; gene therapy; retinal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1401-1450 on page 29 of 62.

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