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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research on Functional Genomics and Genome Editing in Plants

edited by

Rushil Ramesh Mandlik

submission deadline 30 Apr 2027 | Viewed by 17 | Submission Open

Keywords: CRISPR/Cas; genome editing; functional genomics; plant biotechnology; gene regulation; base editing; prime editing; gene overexpression; multi-omics; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Melanoma: Molecular Mechanism and Therapy, 2nd Edition

edited by

Balázs Margit

submission deadline 30 May 2027 | 3 articles | Viewed by 4133 | Submission Open

Keywords: melanoma progression; melanoma metastasis; molecular background; targeted therapies; immunotherapy; acquired drug resistance; prognostic and predictive markers; therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Molecular Evolution of the Vertebrate Immune System

edited by

Pierre Pontarotti

submission deadline 30 May 2027 | 1 articles | Viewed by 1386 | Submission Open

Keywords: immune system; molecular evolution; V (D) J recombination; RAG transposon; comparative genomics

(This special issue belongs to the Section Molecular Biology)

Agronomic Regulation of Crop Environmental Adaptation and Grain Safety: Physiological and Molecular Mechanisms

edited by

Ligeng Jiang

and

Sun Yujun

submission deadline 30 May 2027 | Viewed by 24 | Submission Open

Keywords: agronomic management; environmental adaptation; molecular regulation; physiological and biochemical mechanisms; crop quality formation; plant-soil-microbe interactions; heavy metal detoxification; nitrogen-use efficiency; photosynthetic efficiency

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology on Environmental Microorganisms

edited by

Mariusz Cycoń

submission deadline 31 May 2027 | 3 articles | Viewed by 1889 | Submission Open

Keywords: environmental microbiology; metagenomics; microbial interactions; phage–host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Advanced Drug Delivery Systems: From Nanocarrier Design to Translation

edited by

Krishna Jadhav

and

Satish Rojekar

submission deadline 31 May 2027 | Viewed by 123 | Submission Open

Keywords: nanocarriers; stimuli-responsive; targeted delivery; biocompatibility; scale-up; nanomedicine

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms Linking Environmental Pollutant Exposure to Human Health and Development

edited by Agnieszka Ścibior and

Juan Llopis

submission deadline 31 May 2027 | Viewed by 82 | Submission Open

Keywords: environmental pollutants; molecular toxicology; developmental toxicology; particulate matter; metals and metalloids; pesticides; persistent organic pollutants; PFAS; environmental pharmaceuticals; microplastics; nanoplastics; mixture toxicity; adverse outcome pathways; human biomonitoring; toxicokinetics; oxidative stress; genotoxicity; epigenetics; endocrine disruption; neurodevelopment; human health risk assessment

(This special issue belongs to the Section Molecular Toxicology)

Functional Polymeric Biomaterials: From Molecular Engineering to Biomedical Applications

edited by

Joanna Rydz

Marta Musioł

, Khadar Duale and

Barbara Zawidlak-Węgrzyńska

submission deadline 1 Jun 2027 | Viewed by 51 | Submission Open

Keywords: polymeric biomaterials; biodegradable polymers; molecular design; AI-driven materials design; structure–property relationships; biomolecule–material interactions; biocompatibility; drug delivery systems; tissue engineering; regenerative medicine

(This special issue belongs to the Section Materials Science)

The Chitosan Biomaterials: Advances and Challenges, 3rd Edition

edited by

Lacramioara Popa

Mihaela Violeta Ghica

and Cristina Elena Dinu-Pirvu

submission deadline 20 Jun 2027 | 1 articles | Viewed by 1604 | Submission Open

Keywords: chitosan; chitosan biomaterials; chitosan derivatives; drug delivery; wound healing; tissue regeneration; dentistry; smart biomaterials

(This special issue belongs to the Section Materials Science)

Molecular Progression of Genome-Related Diseases: 2nd Edition

edited by

Salvatore Saccone

submission deadline 25 Jun 2027 | 6 articles | Viewed by 22463 | Submission Open

Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health

(This special issue belongs to the Section Molecular Genetics and Genomics)

Effects of Bioactive Compounds in Cardiovascular and Neurological Diseases

edited by

Paul-Mihai Boarescu

submission deadline 30 Jun 2027 | 1 articles | Viewed by 2771 | Submission Open

Keywords: inflammation; oxidative stress; bioactive compounds; cardiovascular diseases; neurological diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Oxidative Stress: New Insights into Disease Pathogenesis, Emerging Preventive Strategies and Novel Therapeutic Approaches

edited by Fabio Vivarelli and

Donatella Canistro

submission deadline 30 Jun 2027 | 2 articles | Viewed by 2577 | Submission Open

Keywords: metabolism; inflammation; oxidative stress; diabetes; natural oxidative stress modulators; novel preventive/therapeutic strategies; ageing; cardiovascular diseases; regenerative medicine; neurodegeneration; environmental exposure; cancer

(This special issue belongs to the Section Molecular Biology)

From Molecular Understanding to Ecological Significance: Understanding Marine Reproductive Biology

edited by

Zohaib Noor

submission deadline 30 Jun 2027 | Viewed by 440 | Submission Open

Keywords: reproductive biology; gametogenesis; bivalves reproduction; biodiversity; endocrine regulation; gametogenesis; molecular signaling; genomics; fertilization; population dynamics; ecological resilience

(This special issue belongs to the Section Molecular Biology)

Sex and Gender Medicine: New Horizons in Human Health and Disease

edited by

Alessandra Carè

, Eliana Ferroni and

Elena Ortona

submission deadline 30 Jun 2027 | 1 articles | Viewed by 382 | Submission Open

Keywords: sex differences; gender medicine; personalized medicine; health inequities; intersectionality; precision health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticle Toxicity: Beyond Chemical Composition—the Critical Role of Physicochemical Properties

edited by

Karen Khachatryan

submission deadline 31 Jul 2027 | 1 articles | Viewed by 1221 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; physicochemical properties; risk assessment; reactive oxygen species (ROS); protein corona; cellular uptake; regulatory science; safe-by-design

(This special issue belongs to the Section Molecular Toxicology)

Selected Papers from the HSG-2025 Conference

edited by

Marsel Kabilov

submission deadline 31 Jul 2027 | 1 articles | Viewed by 887 | Submission Open

Keywords: metagenomics; genomics; metabarcoding; next-generation sequencing; transcriptomics; translatomics; NGS data analysis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Machine Learning in RNA and Chromatin Dynamics

edited by Haopeng Yu

submission deadline 31 Jul 2027 | Viewed by 560 | Submission Open

Keywords: machine learning; chromatin architecture; RNA dynamics; genomic foundation models; computational biology

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Aging: Genetics, Epigenetics and Biomolecular Interventions

edited by

Shin Murakami

submission deadline 31 Jul 2027 | Viewed by 45 | Submission Open

Keywords: aging; biomarkers; bioactive nutrients; centenarians; life-extending interventions; exercise; red wine; stress resistance and metabolism; age-related diseases

(This special issue belongs to the Section Molecular Biology)

Advances in Viral Cancers and Virotherapies

edited by

Maria C. White

and

Brent A. Stanfield

submission deadline 31 Jul 2027 | Viewed by 37 | Submission Open

Keywords: oncogenic virus; oncolytic virus; lymphomagenesis; oncogenesis; immunotherapy; immune modulation; drug resistance; transformation; inflammation; DNA repair

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Mechanisms of Neuroendocrine Tumors

edited by

Luigi Pio Guerrera

and Michele Ghidini

submission deadline 31 Jul 2027 | Viewed by 23 | Submission Open

Keywords: rare tumours; neuroendocrine neoplasms; translational research; gut microbiome; liquid biopsy; novel targets; VHL1; predictive biomarkers; tumour microenvironment

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Bioinformatics Analysis of Single Cell and Spatial Multi-Omics

edited by Fahong Yu

submission deadline 20 Aug 2027 | 1 articles | Viewed by 1298 | Submission Open

Keywords: bioinformatics; single-cell omics; spatial multi-omics; matabolomics; genomics; transcriptomics; proteomics; next-generation sequencing techniques

(This special issue belongs to the Section Molecular Informatics)

Molecular Mechanisms, Biomarkers, and Translational Research in Stroke and Neurotrauma

edited by Kang-Ho Choi

submission deadline 30 Aug 2027 | Viewed by 17 | Submission Open

Keywords: stroke; cerebrovascular disease; endovascular thrombectomy; prognostic biomarkers; molecular pathophysiology; neurovascular imaging; lipidomic metabolites; experimental neurology; clinical trial methodologies; novel therapeutic approaches

(This special issue belongs to the Section Molecular Neurobiology)

Research on Genomics of Crop Stress Tolerance

edited by

Xi Zhu

submission deadline 31 Aug 2027 | 2 articles | Viewed by 997 | Submission Open

Keywords: crop stress tolerance; genomic research; molecular mechanisms; multi-omics approaches; epigenetic modifications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Targeting in Nanoparticle Systems: Precision Therapy, Detoxification, and Environmental Remediation

edited by

Adelina-Gabriela Niculescu

and Dan Eduard Mihəiescu

submission deadline 31 Aug 2027 | Viewed by 428 | Submission Open

Keywords: nanoparticles; nanocomposites; molecular targeting; stimuli-responsive materials; magnetic nanoparticles; surface functionalization; precision therapy; detoxification; decontamination; environmental remediation

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Molecular and Cellular Biology in Neuroscience

edited by

Keigo Kohara

submission deadline 31 Aug 2027 | 1 articles | Viewed by 197 | Submission Open

Keywords: molecular neuroscience; cellular neurobiology; imaging; synaptic plasticity; optogenetics; brain visualization; signal transduction; developmental molecular and cellular biology in neuroscience; neurological disorders

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Members’ Collection Series in “Cardiovascular Biochemistry”

edited by

Michał Pruc

and

Łukasz Szarpak

submission deadline 31 Aug 2027 | Viewed by 17 | Submission Open

Keywords: cardiovascular biomarkers; molecular biomarkers; cardiovascular diseases; acute coronary syndromes; myocardial infarction; heart failure; atherosclerosis; inflammation; immunology; multi-omics; precision medicine; molecular mechanisms; biomarker discovery; biomarker validation; translational medicine; artificial intelligence

(This special issue belongs to the Section Biochemistry)

Displaying special issue 3001-3050 on page 61 of 61.

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