Special Issue "Protein Folding and Misfolding ---- Structure and Functions"
Deadline for manuscript submissions: closed (28 February 2021).
Interests: molecular biophysics; quantitative and synthetic biology; protein engineering; protein folding, binding and function; protein–DNA interactions; molecular mechanisms of transcription; single molecule fluorescence; statistical mechanics; computational chemistry and biology; optical spectroscopy; nuclear magnetic resonance spectroscopy (NMR); atomic force microscopy (AFM); laser spectroscopy and ultrafast kinetics
Interests: protein folding; protein dynamics and disorder; protein-protein recognition
Special Issues and Collections in MDPI journals
Special Issue in Life: Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins, Volume II
Special Issue in Life: Function and Dysfunction of Phase Separations and Transitions Driven by Intrinsically Disordered Protein Regions
Nearly all biological processes rely on the conformational states of interacting macromolecules. It is, therefore, not surprising that the study of protein folding and misfolding has played a central role in chemistry and biology. In particular, substantial experimental and theoretical efforts have been devoted to understanding the general rules of folding, as well as to deciphering the mechanisms that lead to misfolding and related diseases. Furthermore, the discovery that a large fraction of the proteome is essentially disordered, while being fully functional, has revolutionized our comprehension of the structure–function relationships, posing the description of intrinsically disordered proteins as a key problem in modern science.
This Special Issue focuses on recent studies that contribute to our understanding of protein folding and misfolding, as well as on the role of intrinsic disorder in protein functions. Original research articles and reviews on these and related topics are welcome in this Special Issue.
Prof. Dr. Victor Muñoz
Prof. Dr. Stefano Gianni
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- protein folding;
- energy landscape;
- molecular dynamics simulation;
- chemical kinetics;
- energy barriers;
- down-hill folding;
- protein misfolding;
- protein unfolding;
- amyloid structure;
- degenerative diseases;
- oligomer toxicity;
- intrinsic disorder;
- intrinsically disordered proteins;
- folding upon binding