Special Issue "Pluripotent Stem Cell Technology for Disease Modeling, Drug Discovery and Regenerative Medicine"
Deadline for manuscript submissions: closed (29 February 2016).
Interests: stem cell biology; regenerative medicine; neuroscience; glia; oligodendrocyte; astrocyte; microglia
Special Issues and Collections in MDPI journals
Stem cell technology represents a powerful tool for regenerative medicine. The most remarkable breakthrough in stem cell research is the success of generating induced pluripotent cells by reprogramming of somatic cells to a pluripotent state via defined factors. Stem cell research is advancing the understanding of the development of organisms from single cells, fundamental properties and characteristics of pluripotent cells, analysis of differentiation pathways induced in stem cells by endogenous and exogenous factors, conversion and induction of differentiated cells to become pluripotent cells, trans-differentiation by direct lineage reprogramming, and therapeutic applications of stem cells to regenerate or replace damaged cells. Stem cell research provides hope for the prevention and treatment of many debilitating and currently untreatable diseases. In addition, stem cells can be used for diagnostics, toxicological and pharmaceutical testing, understanding fundamental disease processes, drug development and delivery, and tissue engineering. This Special Issue will feature a collection of interdisciplinary work at the interface of stem cell technology, tissue engineering, drug discovery, and regenerative medicine. We welcome contributions from a dynamic multidisciplinary group of investigators, including chemists, biologists, engineers, and physicians, addressing basic and translational issues in tissue engineering and regenerative medicine, and using stem cells to study and treat a broad variety of diseases. Topics may include: stem cell-based approaches and technology platforms for drug discovery, tissue engineering, and regeneration, modeling of development and aging, pluripotent stem cells for disease modeling and drug discovery, tissue engineering, biotechnology, and stem cell pharmacology/toxicology. The mission is to advance the fundamental knowledge of stem cells and their differentiation pathways, understand how stem cells interact with tissues and organ systems of the body, and develop stem cell-based therapies to treat human diseases and injuries.
Prof. Dr. Wenbin Deng
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- stem cell technology
- gene and cell therapy
- drug discovery and delivery
- transcriptional and mitochondrial regulation of cell fate
- cellular plasticity; direct cell lineage/fate reprogramming
- stem cell differentiation
- regenerative medicine