Special Issue "Molecular Research on Stress Response and Ocular Homeostasis"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 10 May 2020.
Interests: retina; hypoxia response; myopia; optogenetics
Special Issues and Collections in MDPI journals
Stress response is a fundamental cellular reaction contributing to developmental processes, tissue homeostasis, and organ pathogenesis. Physiologically, individual organs maintain their homeostasis, reacting to various stresses such as hypoxia, inflammation, and starvation. The eye is the organ which specifically exists in order to receive light and convert it to a signal. Thus, individual cells protect their functions from the distinctive microenvironment in respective ocular components including the cornea, the crystalline lens, the retina, and the uvea. Not only intraocular systems but also inter-organ systems such as the eye–gut axis utilize cellular stress response to maintain local and systemic homeostasis. Molecular components including, but not limited to, stress-responsive transcriptional factors such as hypoxia-inducible factors (HIFs), nuclear factor erythroid 2-related factor 2 (Nrf2), and nuclear factor-kappa B (NF-kB) have been revealed to play a critical role in cellular stress response. Dysfunction or rather ectopic activation of molecules in charge of cellular stress response can be observed in the pathophysiological process of multiple ocular components. This Special Issue will focus on ocular stress response in molecular, cellular, local, and systemic levels. The response and related molecules are conserved between species; therefore, the scope includes a large extent from the basic biological sciences to human diseases.
Assoc. Prof. Toshihide Kurihara
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Hypoxia response
- Oxidative stress
- Energy homeostasis
- Light exposure